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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000371054':
INSL6 - Insulin-like peptide INSL6 A chain; May have a role in sperm development and fertilization.
[a.k.a. AAF29604.1, NP_009110.2, INSL6-201]
2) '9606.ENSP00000426120':
GRAMD2B - GRAM domain containing 2B.
[a.k.a. NP_001139792, XM_017009781.1, ENSP00000421494]
3) '9606.ENSP00000266659':
GLIPR1 - Glioma pathogenesis-related protein 1; GLI pathogenesis related 1; Belongs to the CRISP family.
[a.k.a. XP_011536077, ENST00000456650, Protein RTVP-1]
4) '9606.ENSP00000354995':
ABCG1 - ATP-binding cassette sub-family G member 1; Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta- hydroxycholesterol and this transport is coupled to hydrlysis of ATP. The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta- hydroxycholesterol ; Belongs to the ABC transporter superfamily. ABCG [...]
[a.k.a. WHITE1, NM_004915.3, BAB13728.2]
5) '9606.ENSP00000302716':
MUC17 - Mucin-17; Probably plays a role in maintaining homeostasis on mucosal surfaces.
[a.k.a. MUC-3, Q685J3, ENST00000436719]
6) '9606.ENSP00000339830':
TMEM220 - Transmembrane protein 220.
[a.k.a. NP_001004313, OTTHUMG00000178043, XP_011522137]
7) '9606.ENSP00000296518':
GUCY1A1 - Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
[a.k.a. XM_006714196, guanylate cyclase 1, soluble, alpha 3, 2982]
8) '9606.ENSP00000312741':
CAMKK2 - Calcium/calmodulin-dependent protein kinase kinase 2; Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals ( [...]
[a.k.a. 6BQQ, R-HSA-388396, R-HSA-9619229]
9) '9606.ENSP00000427120':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000310036':
CD34 - Hematopoietic progenitor cell antigen CD34; Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
[a.k.a. Q5JTA5, ENST00000367037, 947]
11) '9606.ENSP00000382090':
CLDN14 - Claudin-14; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
[a.k.a. NM_001146079, AAR05859.1, AAG60052.1]
12) '9606.ENSP00000368924':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
13) '9606.ENSP00000332973':
SMAD3 - Mothers against decapentaplegic homolog 3; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP- 1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and m [...]
[a.k.a. R-HSA-170834, B7Z6M9, R-HSA-3304349]
14) '9606.ENSP00000351671':
CCL20 - C-C motif chemokine 20; Acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions. The ligand- receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and various autoimmune diseases. CCL20 acts as a chemotactic factor that attracts lymphocytes and, slig [...]
[a.k.a. R-HSA-388396, MIP-3-alpha, R-HSA-162582]
15) '9606.ENSP00000362994':
TRAF1 - TNF receptor-associated factor 1; Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin- protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
[a.k.a. ENSG00000056558, ENST00000546084.5, AK295959]
16) '9606.ENSP00000370128':
SLC7A1 - High affinity cationic amino acid transporter 1; High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues.
[a.k.a. ecotropic retroviral receptor, uc001uso.4, R-HSA-352230]
17) '9606.ENSP00000398560':
SPATA13 - Spermatogenesis-associated protein 13; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
[a.k.a. ENST00000382108, CCDS66518, NM_001286794.1]
18) '9606.ENSP00000349143':
BTN2A2 - Butyrophilin subfamily 2 member A2; Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. Belongs to the immunoglobulin superfamily. BTN/MOG family.
[a.k.a. CH471087, XM_005248797.3, EAW55564.1]
19) '9606.ENSP00000358765':
TPBG - Trophoblast glycoprotein; May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
[a.k.a. 5T4AG, CCDS4995.1, AJ012159]
20) '9606.ENSP00000258534':
DRAM1 - DNA damage-regulated autophagy modulator protein 1; Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.
[a.k.a. UPI0001914F96, BAH12666.1, DRAM1-205]
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