searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000377854':

LHX6 - LIM/homeobox protein Lhx6; Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex (By similarity). [a.k.a. ENST00000558672, CCDS6837, NM_199160]

2) '9606.ENSP00000317379':

GLS - Glutaminase kidney isoform, mitochondrial 65 kDa chain; Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain ; Belongs to the glutaminase family. [a.k.a. ENSP00000395596, 3VP1, URS0000D2DDCB]

3) '9606.ENSP00000399518':

SATB1 - DNA-binding protein SATB1; Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and [...] [a.k.a. ENSG00000182568, UPI0003F47A13, Q01826]

4) '9606.ENSP00000370410':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000278200':

IMMP1L - Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. [a.k.a. hsa:196294, XM_005252812.3, ENST00000527184]

6) '9606.ENSP00000370340':

NFIB - Nuclear factor 1 B-type; Transcriptional activator of GFAP, essential for proper brain development. Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. [a.k.a. A0A1B0GVN4, AL137017, NP_001356391]

7) '9606.ENSP00000322270':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000305200':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000325819':

NR2F1 - COUP transcription factor 1; Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG. [a.k.a. ENSP00000325819, HGNC:7975, COUP-TF1]

10) '9606.ENSP00000288840':

SMAD6 - Mothers against decapentaplegic homolog 6; Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF- kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor- activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [a.k.a. MADH6, SMAD 6, R-HSA-162582]

11) '9606.ENSP00000385450':

MAGI1 - Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity). [a.k.a. AIP-3, ENST00000402939, 9223]

12) '9606.ENSP00000365735':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

13) '9606.ENSP00000367471':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000418707':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000346389':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000346829':

WLS - Protein wntless homolog; Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity). [a.k.a. NM_024911, XP_016857879.1, UPI0001F78500]

17) '9606.ENSP00000316891':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000331574':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

19) '9606.ENSP00000260762':

EXOC6 - Exocyst complex component 6; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity). [a.k.a. XM_017016347, EAW50083.1, ENSP00000360598]

20) '9606.ENSP00000263915':

GRB14 - Growth factor receptor-bound protein 14; Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal. [a.k.a. R-HSA-202733, UPI00018816C3, CAB022294]

101 query items

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