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The following proteins in
Homo sapiens
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22 query items
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1) '9606.ENSP00000378414':
SMARCD1 - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). Du [...]
[a.k.a. SWI/SNF complex 60 kDa subunit, Q9Y635, ENST00000547637.1]
2) '9606.ENSP00000417183':
DUSP7 - Dual specificity protein phosphatase 7; Dual specificity protein phosphatase. Shows high activity towards MAPK1/ERK2. Also has lower activity towards MAPK14 and MAPK8. In arrested oocytes, plays a role in meiotic resumption (By similarity). Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in oocytes, probably by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB (By similarity). May also inactivate PRKCA and/or PRKCG (By similarity). Also important in oocytes for normal chromosome alignment on the metaphase plate and [...]
[a.k.a. 3.1.3.16, ENSP00000417183, R-HSA-112409]
3) '9606.ENSP00000233121':
MAPRE3 - Microtubule-associated protein RP/EB family member 3; Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non- centrosomal minus-end microtubules to the Golgi, an important step for polarized [...]
[a.k.a. AC013472, CR541845, EB3]
4) '9606.ENSP00000265734':
CDK6 - Cyclin-dependent kinase 6; Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in initiation and maintenance of cell cycle exit during cell differentiation; prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types (e.g. erythroid and hematopoietic cells). Essential for cel [...]
[a.k.a. Cyclin dependent kinase 6, PLSTIRE, ENST00000265734]
5) '9606.ENSP00000331741':
HOXB2 - Homeobox protein Hox-B2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Proboscipedia subfamily.
[a.k.a. R-HSA-5619507, NP_002136.1, uc002inm.5]
6) '9606.ENSP00000394049':
SLA - Src-like-adapter; Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
[a.k.a. URS0000D6E65C, UPI0003F48048, ENST00000523610]
7) '9606.ENSP00000354607':
FZD5 - Frizzled-5; Receptor for Wnt proteins. Can activate WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 (in vitro); the in vivo situation may be different since not all of these are known to be coexpressed (By similarity). In neurons, activation of WNT7A promotes formation of synapses. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity). A second signaling pathway involving [...]
[a.k.a. 6O39, ENSG00000163251, FZD5-201]
8) '9606.ENSP00000244745':
SOX4 - Transcription factor SOX-4; Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.
[a.k.a. uc003ndi.4, CCDS4547.1, R-HSA-162582]
9) '9606.ENSP00000332151':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000387941':
IFFO2 - Intermediate filament family orphan 2; Belongs to the intermediate filament family.
[a.k.a. ENST00000416166, NM_001136265.1, ENSP00000387941]
11) '9606.ENSP00000272647':
AMMECR1L - AMMECR1-like protein; AMMECR1 like.
[a.k.a. Q6DCA0, XM_011511952, EAW95346.1]
12) '9606.ENSP00000367433':
AJAP1 - Adherens junction-associated protein 1; Plays a role in cell adhesion and cell migration.
[a.k.a. 55966, CAB41245.1, MOT8]
13) '9606.ENSP00000450962':
EMX2 - Homeobox protein EMX2; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
[a.k.a. ENST00000546446, UPI0004620DF9, CCDS7601]
14) '9606.ENSP00000378690':
CALN1 - Calcium-binding protein 8; Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning.
[a.k.a. CALN1-203, AAH20200.1, XM_011516596]
15) '9606.ENSP00000370047':
BNC2 - Zinc finger protein basonuclin-2; Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes.
[a.k.a. HGNC:30988, ENSP00000474832, Q6ZN30]
16) '9606.ENSP00000308330':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
17) '9606.ENSP00000257572':
HRK - Activator of apoptosis harakiri; Promotes apoptosis.
[a.k.a. ENSP00000257572, ENST00000586941, XM_017020146]
18) '9606.ENSP00000318177':
FUBP3 - Far upstream element-binding protein 3; May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.
[a.k.a. ENST00000467100, uc004bzr.2, ENST00000319725]
19) '9606.ENSP00000262844':
AMMECR1 - AMMECR nuclear protein 1.
[a.k.a. HGNC:467, 9949, Q5JYV9]
20) '9606.ENSP00000364585':
RCC2 - Protein RCC2; Multifunctional protein that may effect its functions by regulating the activity of small GTPases, such as RAC1 and RALA. Required for normal progress through the cell cycle, both during interphase and during mitosis. Required for the presence of normal levels of MAD2L1, AURKB and BIRC5 on inner centromeres during mitosis, and for normal attachment of kinetochores to mitotic spindles. Required for normal organization of the microtubule cytoskeleton in interphase cells. Functions as guanine nucleotide exchange factor (GEF) for RALA. Interferes with the activation of RAC1 b [...]
[a.k.a. R-HSA-2555396, NP_061185.1, R-HSA-69278]
22 query items
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