searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000380948':

ITGB2 - Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] [a.k.a. R-HSA-202733, ENST00000302347, E5RHE6]

2) '9606.ENSP00000226574':

NFKB1 - Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] [a.k.a. 4790, AK291450, R-HSA-983705]

3) '9606.ENSP00000463981':

J3QR06_HUMAN - Uncharacterized protein. [a.k.a. ENST00000584948.1, AC134669, UPI000268B09D]

4) '9606.ENSP00000376436':

ETS1 - Protein C-ets-1; Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion; Belongs to the ETS family. [a.k.a. CAA32904.1, XP_011540952.1, CCDS53724]

5) '9606.ENSP00000254667':

PTPRE - Receptor-type tyrosine-protein phosphatase epsilon; Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity). Isoform 1 and isoform 2 act as a negative regulator of FceRI- mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+); Belongs to the protein-tyrosine phosphatase family. Receptor class [...] [a.k.a. ENST00000254667, NP_001310286.1, NP_006495.1]

6) '9606.ENSP00000399700':

PLAC8 - Placenta-specific gene 8 protein; Placenta associated 8. [a.k.a. URS00008B6ED3, HGNC:19254, ENST00000505406.5]

7) '9606.ENSP00000331614':

IKZF1 - DNA-binding protein Ikaros; Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus i [...] [a.k.a. AC124014, CCDS59055.1, ENSP00000342378]

8) '9606.ENSP00000443926':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000476603':

GPRIN3 - G protein-regulated inducer of neurite outgrowth 3; May be involved in neurite outgrowth. [a.k.a. GRIN3, FLJ42625, XM_017008044.1]

10) '9606.ENSP00000235382':

RGS2 - Regulator of G-protein signaling 2; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form. It is involved in the negative regulation of the angiotensin-activated signaling pathway. Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, the [...] [a.k.a. R-HSA-388396, Cell growth-inhibiting gene 31 protein, R-HSA-162582]

11) '9606.ENSP00000360299':

ADGRF1 - Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. [a.k.a. CCDS34471.1, ADGRF1-204, NP_079324.2]

12) '9606.ENSP00000255945':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

13) '9606.ENSP00000425487':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000385727':

MAST4 - Microtubule associated serine/threonine kinase family member 4; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. [a.k.a. XM_017009449, CCDS75254.1, AK131421]

15) '9606.ENSP00000216214':

FAM118A - Protein FAM118A; Family with sequence similarity 118 member A. [a.k.a. XM_017028841, FLJ20635, ENST00000481447.1]

16) '9606.ENSP00000479870':

ALOX5AP - Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes; Belongs to the MAPEG family. [a.k.a. AY619687, R-HSA-556833, UPI0000001056]

17) '9606.ENSP00000484803':

FOXP1 - Forkhead box P1. [a.k.a. BT006643, XP_006713165.1, ENST00000610810]

18) '9606.ENSP00000366243':

CEMIP2 - Cell surface hyaluronidase; Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate- size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate. [a.k.a. A6H8W9, ENSP00000437750, ENST00000396272]

19) '9606.ENSP00000379773':

ZC3H7A - Zinc finger CCCH domain-containing protein 7A; May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 3'- ATA(A/T)-5' motif in the apical loop. [a.k.a. uc002dbl.4, CCDS10550, ENST00000572781]

20) '9606.ENSP00000252445':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

101 query items

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