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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000381382':
TCF4 - Transcription factor 4; Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'- CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'- CCANNTGG-3'.
[a.k.a. ENST00000564999, BAG52974.1, NP_001230163.1]
2) '9606.ENSP00000355354':
SOX15 - Protein SOX-15; Transcription factor that binds to DNA at the 5'-AACAATG-3' consensus sequence (By similarity). Acts as a transcriptional activator and repressor (By similarity). Binds synergistically with POU5F1 (OCT3/4) to gene promoters (By similarity). Binds to the FOXK1 promoter and recruits FHL3, resulting in transcriptional activation of FOXK1 which leads to myoblast proliferation (By similarity). Acts as an inhibitor of myoblast differentiation via transcriptional repression which leads to down-regulation of the muscle-specific genes MYOD and MYOG (By similarity). Involved in t [...]
[a.k.a. uc002ghy.2, CH471108, ENST00000538513.6]
3) '9606.ENSP00000267460':
PELI2 - E3 ubiquitin-protein ligase pellino homolog 2; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL- 1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3- dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.
[a.k.a. EAW80689.1, R-HSA-9020702, R-HSA-446652]
4) '9606.ENSP00000446335':
ZNF362 - Zinc finger protein 362; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
[a.k.a. Zinc finger protein 362, F5H055, FLJ25476]
5) '9606.ENSP00000302913':
SH3D19 - SH3 domain-containing protein 19; May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.
[a.k.a. XP_016863267, AAH85613.2, Q9UFC8]
6) '9606.ENSP00000420095':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000375810':
KLC3 - Kinesin light chain 3; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport; Belongs to the kinesin light chain family.
[a.k.a. ENST00000585434, A0A024R0V3, R-HSA-162582]
8) '9606.ENSP00000323929':
A2M - Alpha-2-macroglobulin; Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the c [...]
[a.k.a. NM_001347424.1, URS00008BF993, R-HSA-162582]
9) '9606.ENSP00000376534':
BAZ2B - Bromodomain adjacent to zinc finger domain protein 2B; May play a role in transcriptional regulation interacting with ISWI; Belongs to the WAL family.
[a.k.a. NP_038478, UPI00020CDF46, 5PGK]
10) '9606.ENSP00000480053':
GPIHBP1 - Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (By similarity). Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (By similarity). Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain [...]
[a.k.a. R-HSA-388396, HDBP1_HUMAN, R-HSA-196854]
11) '9606.ENSP00000221486':
RNASEH2A - Ribonuclease H2 subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. Belongs to the RNase HII family. Eukaryotic subfamily.
[a.k.a. uc002mvg.2, RNHIA, RNHL]
12) '9606.ENSP00000155926':
TRIB2 - Tribbles homolog 2; Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity). Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
[a.k.a. C5FW, AAH02637.1, AC009486]
13) '9606.ENSP00000380271':
RAPGEF4 - Rap guanine nucleotide exchange factor 4; Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).
[a.k.a. B7Z278, ENST00000409036, XM_011510505.3]
14) '9606.ENSP00000414150':
ERG - Transcriptional regulator ERG; Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
[a.k.a. NM_001243429, URS00008B5DC9, ERG-210]
15) '9606.ENSP00000379441':
JMY - Junction-mediating and -regulatory protein; Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin poly [...]
[a.k.a. XM_005248430, ENSG00000152409, ENST00000412001.1]
16) '9606.ENSP00000312678':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
17) '9606.ENSP00000256951':
EMP1 - Epithelial membrane protein 1.
[a.k.a. ENST00000256951, epithelial membrane protein 1, O00681]
18) '9606.ENSP00000002829':
SEMA3F - Semaphorin-3F; May play a role in cell motility and cell adhesion.
[a.k.a. U32172, OTTHUMG00000156806, XM_006713289.3]
19) '9606.ENSP00000219431':
MPG - DNA-3-methyladenine glycosylase; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
[a.k.a. 3MG_HUMAN, 4350, 3-alkyladenine DNA glycosylase]
20) '9606.ENSP00000362082':
CCND3 - G1/S-specific cyclin-D3; Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...]
[a.k.a. AAM51826.1, CAB000116, R-HSA-69278]
101 query items
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