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The following proteins in
Homo sapiens
appear to match your input.
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102 query items
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1) '9606.ENSP00000382697':
ROCK1 - Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. Acts as [...]
[a.k.a. R-HSA-388396, ROCK1-201, NP_005397]
2) '9606.ENSP00000173229':
NTN1 - Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Involved in dorsal root ganglion axon projection towards the spinal cord. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating [...]
[a.k.a. U75586, AC090610, OMIM:601614]
3) '9606.ENSP00000274376':
RASA1 - Ras GTPase-activating protein 1; Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1.
[a.k.a. RASA1_HUMAN, ENSG00000145715, 2M51]
4) '9606.ENSP00000443926':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000166244':
EPHA8 - Ephrin type-A receptor 8; Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin sub [...]
[a.k.a. CAA41980.1, CAB009660, AAH72417.2]
6) '9606.ENSP00000252744':
ZSWIM6 - Zinc finger SWIM domain-containing protein 6; involved in nervous system development, important for striatal morphology and motor regulation.
[a.k.a. XP_024301907, NP_065979.1, XM_024446140.1]
7) '9606.ENSP00000306528':
DESI2 - Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization.
[a.k.a. ENSP00000306528, ENST00000391840, NP_001284675.1]
8) '9606.ENSP00000375919':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000404705':
NAALADL2 - Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2; May be catalytically inactive; Belongs to the peptidase M28 family. M28B subfamily.
[a.k.a. NAALADL2-212, HGNC:23219, ENST00000489729.5]
10) '9606.ENSP00000262231':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
11) '9606.ENSP00000362608':
PIM1 - Serine/threonine-protein kinase pim-1; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain pa [...]
[a.k.a. P11309, uc003onk.4, 5N51]
12) '9606.ENSP00000383599':
WDR47 - WD repeat domain 47.
[a.k.a. UPI0001F782CA, Neuronal enriched MAP-interacting protein, XM_017000697.1]
13) '9606.ENSP00000380781':
NFIX - Nuclear factor 1 X-type; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication; Belongs to the CTF/NF-I family.
[a.k.a. K7ESG9, AAD38240.1, NP_001257972.1]
14) '9606.ENSP00000368523':
DNAJC15 - DnaJ homolog subfamily C member 15; Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9.
[a.k.a. ENST00000474320, AAH95400.1, uc001uyy.4]
15) '9606.ENSP00000265734':
CDK6 - Cyclin-dependent kinase 6; Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in initiation and maintenance of cell cycle exit during cell differentiation; prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types (e.g. erythroid and hematopoietic cells). Essential for cel [...]
[a.k.a. Cyclin dependent kinase 6, PLSTIRE, ENST00000265734]
16) '9606.ENSP00000329638':
ZNF804B - Zinc finger protein 804B.
[a.k.a. ENSP00000329638, NP_857597.1, A4D1E1]
17) '9606.ENSP00000296088':
SNRK - SNF-related serine/threonine-protein kinase; May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.
[a.k.a. XM_005265245.3, SNRK-207, ENST00000429705]
18) '9606.ENSP00000334538':
SREK1 - Splicing regulatory glutamine/lysine-rich protein 1; Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity).
[a.k.a. NM_001323527.2, SREK1-212, ENST00000524111]
19) '9606.ENSP00000438468':
HHAT - Protein-cysteine N-palmitoyltransferase HHAT; Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling. May bind GTP; Belongs to the membrane-bound acyltransferase family. HHAT subfamily.
[a.k.a. NM_018194.6, AK316190, ENSP00000442625]
20) '9606.ENSP00000257749':
BACH2 - Transcription regulator protein BACH2; Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1. Positively regulates the nuclear import of actin (By similarity). Is a key regulator of adaptive immunity, crucial for the maintenance of regulatory T-cell function and B-cell maturation ; Belongs to the bZI [...]
[a.k.a. ENST00000470301.5, ENSP00000345642, NM_021813]
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