searching ... STRING: functional protein association networks

Version:
12.0

The following proteins in Homo sapiens appear to match your input.
Please review the list, then click 'Continue' to proceed.

<- Back ⤓ Mapping Continue ->

101 query items

showing page 1 of 6 • first • previous • next • last

1) '9606.ENSP00000383986':

CDCA7L - Cell division cycle-associated 7-like protein; Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38- kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. [a.k.a. ENSP00000363045, A4D141, CDCA7L-204]

2) '9606.ENSP00000381382':

TCF4 - Transcription factor 4; Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'- CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'- CCANNTGG-3'. [a.k.a. ENST00000564999, BAG52974.1, NP_001230163.1]

3) '9606.ENSP00000332151':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000366487':

ARL5B - ADP-ribosylation factor-like protein 5B; Binds and exchanges GTP and GDP. [a.k.a. ENSP00000366487, NM_178815.3, XM_005252401]

5) '9606.ENSP00000403323':

ARHGAP27 - Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). [a.k.a. ENST00000582826, ENSP00000431722, XM_006721745]

6) '9606.ENSP00000324842':

AACS - Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity); Belongs to the ATP-dependent AMP-binding enzyme family. [a.k.a. ENST00000536752, ENSP00000442691, ENSP00000392967]

7) '9606.ENSP00000296518':

GUCY1A1 - Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. [a.k.a. XM_006714196, guanylate cyclase 1, soluble, alpha 3, 2982]

8) '9606.ENSP00000445829':

SLC39A11 - Zinc transporter ZIP11; Functions as a cellular zinc transporter. [a.k.a. NP_001339621, XM_006721757, URS00008B89CD]

9) '9606.ENSP00000379294':

FAM172A - Cotranscriptional regulator FAM172A; Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity; Belongs to the FAM172 family. [a.k.a. AK295879, XP_016865442, XP_011541973.1]

10) '9606.ENSP00000358397':

FAM72B - Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. [a.k.a. ENSP00000347368, ENSP00000482799, URS00008B51B3]

11) '9606.ENSP00000223293':

GIMAP2 - GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself. [a.k.a. Q96L25, 2XTN, UPI0000EE7AD6]

12) '9606.ENSP00000346173':

ETFB - Electron transfer flavoprotein subunit beta; Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF- ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role. [a.k.a. NP_001976, HPA018921, XP_024307186.1]

13) '9606.ENSP00000219022':

OLFM4 - Olfactomedin-4; May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. [a.k.a. AAI17330.1, GC1, NM_006418.4]

14) '9606.ENSP00000482457':

PLCG2 - 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling. [a.k.a. UPI000246730C, R-HSA-983705, PLC-IV]

15) '9606.ENSP00000255945':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000358098':

C1orf54 - Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54. [a.k.a. NP_001287968.1, UPI000007219A, NP_001287968]

17) '9606.ENSP00000424079':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000342295':

ANKRD55 - Ankyrin repeat domain 55. [a.k.a. AC016585, KF457925, XM_017009853.1]

19) '9606.ENSP00000354387':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

20) '9606.ENSP00000311825':

CTBP2 - C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. [a.k.a. XP_016871245, AL596261, 1488]

101 query items

showing page 1 of 6 • first • previous • next • last

<- Back ⤓ Mapping Continue ->

© STRING Consortium 2023

Credits

Access

Info

About