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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000384876':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
2) '9606.ENSP00000484181':
TBC1D3K - TBC1 domain family member 3K; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
[a.k.a. TBC1D3E, XM_011524173, 101060351]
3) '9606.ENSP00000381216':
KHSRP - Far upstream element-binding protein 2; Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue- specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machiner [...]
[a.k.a. M0QYG1, FUBP2, R-HSA-450604]
4) '9606.ENSP00000484146':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000379011':
CPT1B - Carnitine O-palmitoyltransferase 1, muscle isoform; Carnitine palmitoyltransferase 1B.
[a.k.a. ENSP00000409342, ENSP00000353945, EAW73568.1]
6) '9606.ENSP00000278379':
SLC1A2 - Excitatory amino acid transporter 2; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminatin [...]
[a.k.a. ENST00000395750, P43004, ENST00000647104]
7) '9606.ENSP00000482630':
TBC1D3H - TBC1 domain family member 3H; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
[a.k.a. HGNC:30708, XM_011525172.2, OMIM:610811]
8) '9606.ENSP00000269720':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000257336':
BIVM - Basic, immunoglobulin-like variable motif containing.
[a.k.a. NP_001153068.1, Q86UB2, uc001vps.4]
10) '9606.ENSP00000402154':
MEF2B - Myocyte-specific enhancer factor 2B; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.
[a.k.a. BORCS8-MEF2B, ENSP00000390100, MEF2B-202]
11) '9606.ENSP00000478683':
TBC1D3 - TBC1 domain family member 3; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.
[a.k.a. NM_001123391.3, OTTHUMG00000188487, TBC1D3A]
12) '9606.ENSP00000482345':
TBC1D3C - TBC1 domain family member 3C.
[a.k.a. XP_011523116, XM_006721904.2, XP_006721970.1]
13) '9606.ENSP00000363081':
DKK1 - Dickkopf-related protein 1; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner [...]
[a.k.a. AAG15544.1, SK, R-HSA-162582]
14) '9606.ENSP00000290953':
AGRP - Agouti-related protein; Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
[a.k.a. 1MR0, agouti related protein homolog (mouse), DQ374394]
15) '9606.ENSP00000376822':
STEAP3 - Metalloreductase STEAP3; Endosomal ferrireductase required for efficient transferrin- dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
[a.k.a. AC016736, CAH56204.1, ENST00000393110]
16) '9606.ENSP00000253079':
CCDC62 - Coiled-coil domain-containing protein 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR.
[a.k.a. Q6P9F0, XP_006719706.1, Coiled-coil domain containing 62]
17) '9606.ENSP00000478426':
TBC1D3D - TBC1 domain family member 3D; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
[a.k.a. NM_001291465.1, A0A087WVF3, XP_011522478.1]
18) '9606.ENSP00000345341':
PTGES2 - Prostaglandin E synthase 2 truncated form; Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2).
[a.k.a. ENSP00000345341, PTGES2-208, R-HSA-556833]
19) '9606.ENSP00000270238':
LMTK3 - Serine/threonine-protein kinase LMTK3; Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription. Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).
[a.k.a. XP_011524714, UPI000013D87D, XP_011524713.1]
20) '9606.ENSP00000284984':
ADAMTS1 - A disintegrin and metalloproteinase with thrombospondin motifs 1; Cleaves aggrecan, a cartilage proteoglycan, at the '1938- Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.
[a.k.a. CH471079, ENSG00000154734, KIAA1346]
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