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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000393097':
GABRA1 - Gamma-aminobutyric acid receptor subunit alpha-1; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel. The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By si [...]
[a.k.a. NM_001127645, GABRA1-219, ENSP00000430895]
2) '9606.ENSP00000326806':
NCBP2 - Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The C [...]
[a.k.a. R-HSA-162587, URS0000EC2179, R-HSA-191859]
3) '9606.ENSP00000363191':
ROMO1 - Reactive oxygen species modulator 1; Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation; Belongs to the MGR2 family.
[a.k.a. Q9H1N2, Protein MGR2 homolog, ROS modulator 1]
4) '9606.ENSP00000395083':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000475686':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000282841':
GGPS1 - Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
[a.k.a. NP_001358406, UPI000040E13B, 2Q80]
7) '9606.ENSP00000483825':
IKBKG - NF-kappa-B essential modulator; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activati [...]
[a.k.a. NP_001093326.2, IPD2, CHEMBL4967]
8) '9606.ENSP00000363205':
NFS1 - Cysteine desulfurase, mitochondrial; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters. May be involved in the biosynthesis of molybdenum cofactor; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
[a.k.a. NM_021100.5, ENST00000374085.5, AJ010952]
9) '9606.ENSP00000365744':
PRR3 - Proline-rich protein 3; Proline rich 3.
[a.k.a. NM_025263, AAI26456.1, U63336]
10) '9606.ENSP00000356785':
NME7 - Nucleoside diphosphate kinase 7; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
[a.k.a. NP_932076.1, R-HSA-69278, ENST00000493481]
11) '9606.ENSP00000345405':
SPRED3 - Sprouty-related, EVH1 domain-containing protein 3; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase.
[a.k.a. OTTHUMG00000182082, NP_001035987, K7EPU5]
12) '9606.ENSP00000369614':
CNTROB - Centrobin; Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
[a.k.a. ENST00000576536.1, LIP8, AF331638]
13) '9606.ENSP00000250495':
NEDD8 - NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
[a.k.a. R-HSA-170834, R-HSA-8951664, uc001wnn.3]
14) '9606.ENSP00000386772':
GPATCH11 - G-patch domain containing 11.
[a.k.a. NP_001358789, XP_016859237.1, ENSP00000368482]
15) '9606.ENSP00000403400':
CCPG1 - Cell cycle progression protein 1; Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation. Belongs to the CCPG1 family.
[a.k.a. ENST00000563171, ENST00000564663, CCDS55966.1]
16) '9606.ENSP00000298743':
GAS1 - Growth arrest-specific protein 1; Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
[a.k.a. P54826, CCDS6674, AAI36587.1]
17) '9606.ENSP00000357901':
SCNM1 - Sodium channel modifier 1; Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
[a.k.a. TNFAIP8L2-SCNM1, SCNM1-204, ENST00000461862]
18) '9606.ENSP00000377504':
ZNF414 - Zinc finger protein 414; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
[a.k.a. ENST00000596772, CCDS12205.1, NP_001139647.1]
19) '9606.ENSP00000466134':
PRKCSH - Glucosidase 2 subunit beta; Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity).
[a.k.a. PRKCSH-202, ENSP00000465821, NM_001289102.1]
20) '9606.ENSP00000303434':
USP38 - Ubiquitin carboxyl-terminal hydrolase 38; Deubiquitinating enzyme exhibiting a preference towards 'Lys- 63'-linked ubiquitin chains; Belongs to the peptidase C19 family.
[a.k.a. C19.056, NP_001277254.1, XP_011530662.1]
101 query items
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