searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000395654':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

2) '9606.ENSP00000367727':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

3) '9606.ENSP00000305714':

BMP1 - Bone morphogenetic protein 1; Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX. [a.k.a. procollagen C-endopeptidase, ENST00000354870.5, BMP1-214]

4) '9606.ENSP00000260653':

SIX3 - Homeobox protein SIX3; Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon. Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression. In addition, Six3 activity is re [...] [a.k.a. AF092047, ENST00000260653.4, OTTHUMG00000152424]

5) '9606.ENSP00000328090':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000384620':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

7) '9606.ENSP00000310561':

ARHGAP32 - Rho GTPase-activating protein 32; GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity). Belongs to the PX domain-containing GAP family. [a.k.a. MGC1892, KIAA0712, HPA038382]

8) '9606.ENSP00000341282':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000420616':

TFDP2 - Transcription factor Dp-2; Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell- cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters. [a.k.a. R-HSA-170834, ENST00000317075, XM_017007091.1]

10) '9606.ENSP00000303540':

SCN1A - Sodium channel protein type 1 subunit alpha; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Plays a key role in brain, probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neurons induces pain without neurogenic inflammatio [...] [a.k.a. NM_001165963.3, NM_001353954.2, NM_001353951.2]

11) '9606.ENSP00000295756':

TRAT1 - T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. [a.k.a. R-HSA-9006925, TRIM, R-HSA-162582]

12) '9606.ENSP00000382330':

RNF222 - Ring finger protein 222. [a.k.a. XM_011523981, NM_001146684.2, ENSG00000189051]

13) '9606.ENSP00000450832':

SIPA1L1 - Signal-induced proliferation-associated 1-like protein 1; Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity). [a.k.a. SPAR1, XM_017021177.1, SI1L1_HUMAN]

14) '9606.ENSP00000284322':

ABI3BP - Target of Nesh-SH3; ABI family member 3 binding protein. [a.k.a. XM_005247300.3, XP_011510955, XP_011510959]

15) '9606.ENSP00000386156':

PYM1 - Partner of Y14 and mago; Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon- exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translatio [...] [a.k.a. Partner of Y14 and mago, NP_001137325.1, ENST00000549939.1]

16) '9606.ENSP00000329880':

PHACTR1 - Phosphatase and actin regulator 1; Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity. Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity). [a.k.a. CH471087, NP_001309238, ENSP00000368631]

17) '9606.ENSP00000483523':

NOL4L - Nucleolar protein 4 like. [a.k.a. ENST00000359676, ENST00000359676.9, XP_024307601.1]

18) '9606.ENSP00000334941':

PTPRU - Receptor-type tyrosine-protein phosphatase U; Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis; Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily. [a.k.a. ENST00000323839, ENSP00000078545, hPTP-J]

19) '9606.ENSP00000458130':

GOLGA8G - Golgin A8 family member G. [a.k.a. XM_024449907, GOLGA8G-207, ENST00000562627]

20) '9606.ENSP00000363001':

SMPDL3B - Acid sphingomyelinase-like phosphodiesterase 3b; Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown. Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro) (By similarity). Belongs to the acid sphingomyelinase family. [a.k.a. sphingomyelin phosphodiesterase acid like 3B, NM_014474, Q5T0Z0]

101 query items

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