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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000400908':
MYBPC1 - Myosin-binding protein C, slow-type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F- actin and native thin filaments, and modifies the activity of actin- activated myosin ATPase. It may modulate muscle contraction or may play a more structural role; Belongs to the immunoglobulin superfamily. MyBP family.
[a.k.a. Slow MyBP-C, MYBPC1-224, CCDS58271.1]
2) '9606.ENSP00000361383':
AIF1L - Allograft inflammatory factor 1-like; Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function.
[a.k.a. UPI00001C1012, ENST00000372305, ENST00000372301]
3) '9606.ENSP00000263174':
PALMD - Palmdelphin.
[a.k.a. CCDS758.1, palmdelphin, PALML]
4) '9606.ENSP00000323584':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000381382':
TCF4 - Transcription factor 4; Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'- CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'- CCANNTGG-3'.
[a.k.a. ENST00000564999, BAG52974.1, NP_001230163.1]
6) '9606.ENSP00000368920':
NHLRC3 - NHL repeat containing 3.
[a.k.a. ENSP00000444581, 387921, NHLRC3-201]
7) '9606.ENSP00000308944':
HLTF - Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
[a.k.a. 4HRH, Q14527, NM_139048.2]
8) '9606.ENSP00000302625':
AXIN2 - Axin-2; Inhibitor of the Wnt signaling pathway. Down-regulates beta- catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.
[a.k.a. NP_001350742.1, AXIN2-208, Conductin]
9) '9606.ENSP00000233712':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000350937':
TES - Testin; Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.
[a.k.a. 2XQN, HPA015269, 26136]
11) '9606.ENSP00000363081':
DKK1 - Dickkopf-related protein 1; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner [...]
[a.k.a. AAG15544.1, SK, R-HSA-162582]
12) '9606.ENSP00000350848':
HMGN5 - High mobility group nucleosome-binding domain-containing protein 5; Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction; Belongs to the HMGN family.
[a.k.a. ENSP00000413402, NM_030763.3, 79366]
13) '9606.ENSP00000365682':
TLE1 - Transducin-like enhancer protein 1; Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full- length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. Belongs to the WD repeat Groucho/TLE family.
[a.k.a. XP_006717326.1, TLE1-206, R-HSA-2122947]
14) '9606.ENSP00000367202':
RECK - Reversion-inducing cysteine-rich protein with Kazal motifs; Functions together with ADGRA2 to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B). Plays a key role in Wnt7-specific responses: required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Acts as a Wnt7-specific coactivator of canonical Wnt signaling by decoding Wnt ligands: acts by interacting specifically with the disordered linker region of Wnt7, thereby conferring ligand selectivity for Wnt7. ADGRA2 is then required to deliver RECK-bound [...]
[a.k.a. Q5W0K6, ST15, B2RNS1]
15) '9606.ENSP00000386884':
CXCR4 - C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade. Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Involved in hematopoiesis and in car [...]
[a.k.a. R-HSA-162587, R-HSA-388396, CD184]
16) '9606.ENSP00000424079':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
17) '9606.ENSP00000242839':
ATP7B - Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
[a.k.a. ENST00000634844.1, ENST00000673923, HPA009137]
18) '9606.ENSP00000399421':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
19) '9606.ENSP00000264674':
MECOM - Histone-lysine N-methyltransferase MECOM; [Isoform 1]: Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.
[a.k.a. CCDS54669.1, 6BW3, R-HSA-9006925]
20) '9606.ENSP00000315949':
HOXD8 - Homeobox protein Hox-D8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
[a.k.a. ENSP00000437431, homeo box D8, ENST00000548663]
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