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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000404151':
CEP170B - Centrosomal protein of 170 kDa protein B; Plays a role in microtubule organization.
[a.k.a. NM_001112726, ENSP00000251181, XM_017021227]
2) '9606.ENSP00000360899':
BEND5 - BEN domain-containing protein 5; Acts as a transcriptional repressor.
[a.k.a. Q7L4P6, ENST00000371833, XM_011542141]
3) '9606.ENSP00000333657':
MX2 - Interferon-induced GTP-binding protein Mx2; Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.
[a.k.a. 4600, ENST00000495892.1, MX2-204]
4) '9606.ENSP00000382684':
MRAP - Melanocortin-2 receptor accessory protein; Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.
[a.k.a. ENSG00000170262, 56246, ENST00000399784.6]
5) '9606.ENSP00000380690':
BICDL1 - BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6- containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity). Belongs to the BICDR family.
[a.k.a. CCDC64, B5MDJ0, XP_006719760]
6) '9606.ENSP00000261881':
TIPIN - TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic st [...]
[a.k.a. NM_017858.2, ENSP00000455656, KF456074]
7) '9606.ENSP00000483254':
HNRNPDL - Heterogeneous nuclear ribonucleoprotein D-like; Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or [...]
[a.k.a. ENST00000507721.5, HNRPDL, NP_112740]
8) '9606.ENSP00000312770':
C2orf69 - UPF0565 protein C2orf69; Chromosome 2 open reading frame 69.
[a.k.a. HGNC:26799, Q8N8R5, UPF0565 protein C2orf69]
9) '9606.ENSP00000435412':
RPS6KA1 - Ribosomal protein S6 kinase alpha-1; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro- apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activa [...]
[a.k.a. R-HSA-388396, hsa:6195, ENST00000531113.5]
10) '9606.ENSP00000421915':
ZNF672 - Zinc finger protein 672; May be involved in transcriptional regulation.
[a.k.a. ENST00000510904.5, Zinc finger protein 672, XM_005270336.1]
11) '9606.ENSP00000360532':
CDC5L - Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
[a.k.a. 5XJC, Cell division cycle 5-like protein, 2DIM]
12) '9606.ENSP00000378399':
WDR89 - WD repeat domain 89.
[a.k.a. MSTP050, WDR89-201, uc059chs.1]
13) '9606.ENSP00000339626':
SLC35E4 - Solute carrier family 35 member E4; Putative transporter.
[a.k.a. NP_001001479.1, AAH40191.1, 339665]
14) '9606.ENSP00000457723':
RNPS1 - RNA-binding protein with serine-rich domain 1; Part of pre- and post-splicing multiprotein mRNP complexes. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the E [...]
[a.k.a. RNPS1-208, ENSP00000457820, ENSP00000380275]
15) '9606.ENSP00000484078':
CCL15 - C-C motif chemokine 15; Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15; Belongs to the intercrine beta (chemokine CC) family.
[a.k.a. NCC3, Macrophage inflammatory protein 5, NCC-3]
16) '9606.ENSP00000263734':
EPAS1 - Endothelial PAS domain-containing protein 1; Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase e [...]
[a.k.a. ENST00000483692, R-HSA-8951664, R-HSA-1234176]
17) '9606.ENSP00000263849':
ZC2HC1A - Zinc finger C2HC-type containing 1A.
[a.k.a. Q96GY0, NR_156423, XP_011515841]
18) '9606.ENSP00000370695':
EXOC1 - Exocyst complex component 1; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
[a.k.a. NP_060731.2, ENST00000509302, ENSP00000334431]
19) '9606.ENSP00000352444':
ZNF33B - Zinc finger protein 33B; May be involved in transcriptional regulation.
[a.k.a. KOX2, NM_001305040.2, Q8NDW3]
20) '9606.ENSP00000175506':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
101 query items
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