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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000404296':
PLEKHA5 - Pleckstrin homology domain containing A5.
[a.k.a. ENST00000538305, XM_011520717, Q9NVK8]
2) '9606.ENSP00000368982':
KATNB1 - Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...]
[a.k.a. ENST00000566785, ENST00000566726, HPA041839]
3) '9606.ENSP00000435233':
TEAD1 - Transcriptional enhancer factor TEF-1; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell [...]
[a.k.a. UPI0001F784CD, BC115398, ENSG00000187079]
4) '9606.ENSP00000312277':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000483283':
H3C11 - H3 clustered histone 11.
[a.k.a. AAH96131.1, HIST1H3I, 5T0M]
6) '9606.ENSP00000277895':
ABLIM1 - Actin-binding LIM protein 1; May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance.
[a.k.a. AL590109, BAA06681.2, ENSP00000376679]
7) '9606.ENSP00000391583':
PARVG - Gamma-parvin; Probably plays a role in the regulation of cell adhesion and cytoskeleton organization; Belongs to the parvin family.
[a.k.a. ENSG00000138964, ENST00000444313.7, CCDS14057.1]
8) '9606.ENSP00000333547':
RAB11B - Ras-related protein Rab-11B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11B plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regul [...]
[a.k.a. Ras-related protein Rab-11B, 9230, AAI10082.1]
9) '9606.ENSP00000346997':
SUV39H2 - Histone-lysine N-methyltransferase SUV39H2; Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric re [...]
[a.k.a. ENSP00000392201, XP_016872126.1, ENST00000354919]
10) '9606.ENSP00000364893':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
11) '9606.ENSP00000424765':
AMOTL2 - Angiomotin-like protein 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC; Belongs to the angiomotin family.
[a.k.a. XP_016862069, ENST00000511759, ENST00000249883]
12) '9606.ENSP00000350718':
TMCC2 - Transmembrane and coiled-coil domains protein 2; May be involved in the regulation of the proteolytic processing of the amyloid precursor protein (APP) possibly also implicating APOE.
[a.k.a. XM_005245685, BAG37022.1, ENST00000648708.1]
13) '9606.ENSP00000368402':
KCTD4 - BTB/POZ domain-containing protein KCTD4; Potassium channel tetramerization domain containing 4.
[a.k.a. NP_940686.2, ENSP00000385144, NX_Q8WVF5]
14) '9606.ENSP00000296529':
TMEM144 - Transmembrane protein 144; Belongs to the TMEM144 family.
[a.k.a. CCDS3799.1, ENSP00000420930, URS0000EB0A1F]
15) '9606.ENSP00000343412':
BABAM2 - BRISC and BRCA1-A complex member 2; Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'- linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integri [...]
[a.k.a. NP_001316042.1, 6H3C, NM_001329113.1]
16) '9606.ENSP00000455698':
STMND1 - Stathmin domain containing 1.
[a.k.a. ENST00000354384, 401236, Stathmin domain containing 1]
17) '9606.ENSP00000349156':
SIAH1 - E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin- mediated degradation of many substrates, including proteins involved in transcription [...]
[a.k.a. UPI0000073CF6, ENST00000565620, hSIAH1]
18) '9606.ENSP00000339299':
TRIO - Triple functional domain protein; Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases. Involved in coordinating actin remodeling, which is necessary for cell migration and growth. In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA- selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity). May act as a regulator of adipogenesis (By similarity).
[a.k.a. R-HSA-388396, UPI000D193823, ENST00000508343.1]
19) '9606.ENSP00000084798':
CA11 - Carbonic anhydrase-related protein 11; Does not have a catalytic activity.
[a.k.a. URS0000D6EB1C, AF067662, CARP2]
20) '9606.ENSP00000421377':
PIEZO2 - Piezo-type mechanosensitive ion channel component 2; Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation.
[a.k.a. ENST00000578145.1, AK127627, FAM38B2]
101 query items
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