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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000418086':
C3orf14 - Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14.
[a.k.a. ENSP00000419977, CC014_HUMAN, HGNC:25024]
2) '9606.ENSP00000251250':
DTWD1 - DTW domain containing 1; Belongs to the DTW family.
[a.k.a. XM_017022422, XP_011520117.1, NM_001144955.1]
3) '9606.ENSP00000370408':
CDX2 - Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA.
[a.k.a. NM_001354700, UPI000013E4C8, CDX2_HUMAN]
4) '9606.ENSP00000264414':
CUL3 - Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cu [...]
[a.k.a. ENST00000409777, R-HSA-8951664, CUL3-206]
5) '9606.ENSP00000396421':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000291565':
PDXK - Pyridoxal kinase; Required for synthesis of pyridoxal-5-phosphate from vitamin B6; Belongs to the pyridoxine kinase family.
[a.k.a. LOC105372824, 2YXT, ENST00000468392]
7) '9606.ENSP00000366271':
KDM2B - Lysine-specific demethylase 2B; Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin liga [...]
[a.k.a. F5H4X4, XM_011538867.3, ENSP00000366271]
8) '9606.ENSP00000267984':
TLNRD1 - Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells.
[a.k.a. hsa:59274, uc002bfz.4, BC084554]
9) '9606.ENSP00000376992':
BCL2L15 - Bcl-2-like protein 15; BCL2 like 15.
[a.k.a. 440603, CCDS30809, FLJ22588]
10) '9606.ENSP00000343273':
KLHL7 - Kelch-like protein 7; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
[a.k.a. UPI0000037B12, XP_006715817, XM_006715754]
11) '9606.ENSP00000356790':
ATP1B1 - Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
[a.k.a. R-HSA-202733, UPI0000126296, ATP1B]
12) '9606.ENSP00000339109':
ANAPC1 - Anaphase-promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Belongs to the APC1 family.
[a.k.a. ANAPC1-206, R-HSA-2555396, R-HSA-174084]
13) '9606.ENSP00000252490':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
14) '9606.ENSP00000419422':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
15) '9606.ENSP00000296135':
LZTFL1 - Leucine zipper transcription factor-like protein 1; Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. Belongs to the LZTFL1 family.
[a.k.a. NR_075080, NM_020347.3, ENST00000319491]
16) '9606.ENSP00000466775':
APOC2 - Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL.
[a.k.a. ENST00000591597, R-HSA-388396, R-HSA-196854]
17) '9606.ENSP00000288532':
COQ5 - 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2); Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
[a.k.a. ENSP00000288532, Coenzyme Q5, methyltransferase, R-HSA-196854]
18) '9606.ENSP00000453508':
TLN2 - Talin-2; As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity).
[a.k.a. NX_Q9Y4G6, XP_016878156, OMIM:607349]
19) '9606.ENSP00000440864':
NR4A1 - Nuclear receptor subfamily 4 group A member 1; Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury (By similarity). ECO:0000250|UniProtKB:P12813.
[a.k.a. 2QW4, R-HSA-9006925, NR4A1-206]
20) '9606.ENSP00000312185':
ELMO1 - Engulfment and cell motility protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
[a.k.a. 2VSZ, ELMO1-208, XP_011513956]
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