searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000424571':

FBN2 - Fibrillin-2 C-terminal peptide; [Fibrillin-2]: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2- containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. Belongs to the fibrillin family. [a.k.a. R-HSA-2129379, HGNC:3604, uc063gqk.1]

2) '9606.ENSP00000367323':

KCNAB2 - Voltage-gated potassium channel subunit beta-2; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes KCNA4 channel closure. Modulates the functional properties of KCNA5 [...] [a.k.a. XM_011542322.2, CCDS55, ENST00000378097]

3) '9606.ENSP00000371348':

TMEM52B - Transmembrane protein 52B. [a.k.a. TMEM52B-201, Transmembrane protein 52B, ENSP00000298530]

4) '9606.ENSP00000312185':

ELMO1 - Engulfment and cell motility protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. [a.k.a. 2VSZ, ELMO1-208, XP_011513956]

5) '9606.ENSP00000393840':

BLOC1S3 - Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. [a.k.a. AAI51152.1, ENST00000588362.1, BLOS3]

6) '9606.ENSP00000463981':

J3QR06_HUMAN - Uncharacterized protein. [a.k.a. ENST00000584948.1, AC134669, UPI000268B09D]

7) '9606.ENSP00000252338':

FAM155B - Transmembrane protein FAM155B; Family with sequence similarity 155 member B. [a.k.a. ENSP00000252338, CXorf63, uc004dxk.4]

8) '9606.ENSP00000364893':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000399700':

PLAC8 - Placenta-specific gene 8 protein; Placenta associated 8. [a.k.a. URS00008B6ED3, HGNC:19254, ENST00000505406.5]

10) '9606.ENSP00000379997':

GAPT - Protein GAPT; Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells (By similarity). Belongs to the GAPT family. [a.k.a. ENST00000318469, ENST00000396776.6, ENST00000511178]

11) '9606.ENSP00000364550':

KDM5C - Lysine-specific demethylase 5C; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys- 27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By [...] [a.k.a. NM_001146702.1, KDM5C-206, UPI00001B0787]

12) '9606.ENSP00000362413':

PGK1 - Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. [a.k.a. ENST00000477335.5, AAI13569.1, 5M1R]

13) '9606.ENSP00000359073':

VAV3 - Guanine nucleotide exchange factor VAV3; Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a [...] [a.k.a. R-HSA-388396, E9PQ97, XM_005270360.2]

14) '9606.ENSP00000357750':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000364907':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000425487':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

17) '9606.ENSP00000428540':

ST3GAL1 - CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values; Belongs to the glycosyltransferase 29 family. [a.k.a. XP_006716680.1, ST3GAL1-210, SIAT4A]

18) '9606.ENSP00000371364':

TMEM156 - Transmembrane protein 156. [a.k.a. XP_011512055, ENST00000381938, ENST00000381938.3]

19) '9606.ENSP00000307259':

P2RY12 - P2Y purinoceptor 12; Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. [a.k.a. R-HSA-388396, BDPLT8, R-HSA-162582]

20) '9606.ENSP00000264463':

CDH10 - Cadherin-10; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. [a.k.a. NX_Q9Y6N8, ENST00000382239, 1008]

101 query items

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