searching ... STRING: functional protein association networks

Version:
12.0

The following proteins in Homo sapiens appear to match your input.
Please review the list, then click 'Continue' to proceed.

<- Back ⤓ Mapping Continue ->

101 query items

showing page 1 of 6 • first • previous • next • last

1) '9606.ENSP00000425093':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

2) '9606.ENSP00000400892':

TESPA1 - Protein TESPA1; Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment. [a.k.a. EAW96800.1, NP_001129502.1, EAW96802.1]

3) '9606.ENSP00000350718':

TMCC2 - Transmembrane and coiled-coil domains protein 2; May be involved in the regulation of the proteolytic processing of the amyloid precursor protein (APP) possibly also implicating APOE. [a.k.a. XM_005245685, BAG37022.1, ENST00000648708.1]

4) '9606.ENSP00000260323':

UNC13C - Protein unc-13 homolog C; May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. May be involved in the regulation of synaptic transmission at parallel fiber - Purkinje cell synapses (By similarity). [a.k.a. XM_017022222.1, AC010867, Q0P613]

5) '9606.ENSP00000284292':

NRGN - NEUG(55-78); Acts as a 'third messenger' substrate of protein kinase C- mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity). Belongs to the neurogranin family. [a.k.a. 4900, ENST00000284292.10, neurogranin (protein kinase C substrate, RC3)]

6) '9606.ENSP00000362399':

STXBP1 - Syntaxin-binding protein 1; Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity). Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. [a.k.a. 6812, ENST00000647107.1, ENST00000636509.2]

7) '9606.ENSP00000348521':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000438388':

KIF1A - Kinesin-like protein KIF1A; Motor for anterograde axonal transport of synaptic vesicle precursors. Also required for neuronal dense core vesicles (DCVs) transport to the dendritic spines and axons. The interaction calcium- dependent with CALM1 increases vesicle motility and interaction with the scaffolding proteins PPFIA2 and TANC2 recruits DCVs to synaptic sites; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily. [a.k.a. AC112784, ENST00000488776.1, BAD92375.1]

9) '9606.ENSP00000480791':

FGF1 - Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with int [...] [a.k.a. 4Q9P, AFGF, 3UD9]

10) '9606.ENSP00000433109':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000402033':

PDZD2 - Processed PDZ domain-containing protein 2; PDZ domain containing 2. [a.k.a. PDZD2-210, AB002298, XP_011512294]

12) '9606.ENSP00000327431':

HBG1 - Hemoglobin subunit gamma 1. [a.k.a. V00514, P69891, Hemoglobin subunit gamma-1]

13) '9606.ENSP00000372654':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000324248':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000306138':

GRM5 - Metabotropic glutamate receptor 5; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol- calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. [a.k.a. 2915, R-HSA-388396, ENSP00000376975]

16) '9606.ENSP00000075120':

SLC2A3 - Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2- deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. [a.k.a. R-HSA-196854, ENST00000486749, ENST00000543435]

17) '9606.ENSP00000362395':

ITM2A - Integral membrane protein 2A. [a.k.a. ENST00000373298, BRICD2A, ENSG00000078596]

18) '9606.ENSP00000262094':

RAB27B - Ras-related protein Rab-27B; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes (By similarity). [a.k.a. XP_024307000.1, ENSG00000041353, UPI0000001268]

19) '9606.ENSP00000388942':

SCRN1 - Secernin-1; Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity). [a.k.a. NM_014766, SCRN1-206, ENSP00000242059]

20) '9606.ENSP00000433642':

FCGR3B - Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. [a.k.a. NP_001231682, CCDS72961.1, FCGR3B-206]

101 query items

showing page 1 of 6 • first • previous • next • last

<- Back ⤓ Mapping Continue ->

© STRING Consortium 2023

Credits

Access

Info

About