searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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109 query items

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1) '9606.ENSP00000426632':

ERBIN - Erbin; Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state. Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion ; Belongs to the LAP (LRR and PDZ) protein family. [a.k.a. ENST00000416865, UPI00017A7193, ENSP00000425728]

2) '9606.ENSP00000229328':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

3) '9606.ENSP00000228434':

CD69 - Early activation antigen CD69; Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. [a.k.a. AIM, AAO63584.1, Z30427]

4) '9606.ENSP00000292303':

CCR5 - C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. [a.k.a. P51681, AIP93481.1, R-HSA-162587]

5) '9606.ENSP00000310796':

THAP2 - THAP domain containing 2. [a.k.a. ENSP00000448904, NM_031435, F8VYP5]

6) '9606.ENSP00000482271':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

7) '9606.ENSP00000358160':

H3C10 - H3 clustered histone 10. [a.k.a. AAH96131.1, 5T0M, 2RI7]

8) '9606.ENSP00000352252':

H3C12 - Histone H3.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [a.k.a. 5XF3, 5XNV, AAH96131.1]

9) '9606.ENSP00000379997':

GAPT - Protein GAPT; Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells (By similarity). Belongs to the GAPT family. [a.k.a. ENST00000318469, ENST00000396776.6, ENST00000511178]

10) '9606.ENSP00000362413':

PGK1 - Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. [a.k.a. ENST00000477335.5, AAI13569.1, 5M1R]

11) '9606.ENSP00000371517':

AMACR - Alpha-methylacyl-CoA racemase; Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2- (4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs ; Belongs to the CoA-transferase III family. [a.k.a. OMIM:604489, ENSG00000242110, NM_203382]

12) '9606.ENSP00000364907':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

13) '9606.ENSP00000356470':

SWT1 - Transcriptional protein SWT1; SWT1 RNA endoribonuclease homolog. [a.k.a. NP_060143, XM_017001528, ENST00000342986]

14) '9606.ENSP00000371364':

TMEM156 - Transmembrane protein 156. [a.k.a. XP_011512055, ENST00000381938, ENST00000381938.3]

15) '9606.ENSP00000173898':

TRO - Trophinin; Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion. [a.k.a. ENST00000474933.6, XP_006724663.1, U04811]

16) '9606.ENSP00000296859':

RAPGEF6 - Rap guanine nucleotide exchange factor 6; Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP. [a.k.a. Rap guanine nucleotide exchange factor 6, RA-GEF-2, A3KN82]

17) '9606.ENSP00000258390':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000479870':

ALOX5AP - Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes; Belongs to the MAPEG family. [a.k.a. AY619687, R-HSA-556833, UPI0000001056]

19) '9606.ENSP00000263056':

MAP3K8 - Mitogen-activated protein kinase kinase kinase 8; Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the regulation of T-helper cell differentiation and IFNG expression in T-cells. Involved in mediating host resistance to bacterial infection through negative regulation of type I interferon (IFN) production. In vitro, activates MAPK/ERK pathway in response to IL1 in an IRAK1-independent manner, leading to up- [...] [a.k.a. Mitogen-activated protein kinase kinase kinase 8, XP_016871196.1, ESTF]

20) '9606.ENSP00000385739':

CEACAM21 - CEA cell adhesion molecule 21; Belongs to the immunoglobulin superfamily. CEA family. [a.k.a. ENST00000482870.6, XM_005278397.4, XM_024451767.1]

109 query items

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