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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000438248':
CALU - Calumenin; Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma- carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity); Belongs to the CREC family.
[a.k.a. calumenin, D6QS59, HM002605]
2) '9606.ENSP00000309142':
PDE12 - 2',5'-phosphodiesterase 12; Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured [...]
[a.k.a. AB115695, Q6L8Q7, F6T1Q0]
3) '9606.ENSP00000457168':
SZT2 - KICSTOR complex protein SZT2; As part of the KICSTOR complex functions in the amino acid- sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by gluc [...]
[a.k.a. ENST00000310739, XR_001737075, chromosome 1 open reading frame 84]
4) '9606.ENSP00000260443':
RSL24D1 - Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity); Belongs to the eukaryotic ribosomal protein eL24 family.
[a.k.a. ribosomal L24 domain containing 1, Large subunit ribosomal protein L24e, AAF86651.1]
5) '9606.ENSP00000340465':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000355927':
RPS6KC1 - Ribosomal protein S6 kinase delta-1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Plays a role in the recruitment of PRDX3 to early endosomes.
[a.k.a. NR_146210, NP_001336589, CCDS44317]
7) '9606.ENSP00000242285':
CLTA - Clathrin light chain A; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Acts as component of the TACC3/ch- TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter- microtubule bridge.
[a.k.a. XM_017014257, uc003zzc.4, Lca]
8) '9606.ENSP00000364847':
MAGED1 - Melanoma-associated antigen D1; Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl- conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression [...]
[a.k.a. ENST00000482599.1, NM_006986, XM_011530835.2]
9) '9606.ENSP00000452123':
SRSF5 - Serine/arginine-rich splicing factor 5; Plays a role in constitutive splicing and can modulate the selection of alternative splice sites; Belongs to the splicing factor SR family.
[a.k.a. U30884, BAG62266.1, BC040209]
10) '9606.ENSP00000431482':
NEDD8-MDP1 - NEDD8-MDP1 readthrough.
[a.k.a. NR_137630.1, ENST00000530579, NEDD8-MDP1-202]
11) '9606.ENSP00000358925':
PSRC1 - Proline/serine-rich coiled-coil protein 1; Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression; Belongs to the PSRC1 family.
[a.k.a. NM_001350237.1, ENST00000369904, XP_016858055]
12) '9606.ENSP00000277632':
MINDY3 - Ubiquitin carboxyl-terminal hydrolase MINDY-3; Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
[a.k.a. ENSP00000277632, ENST00000277632, XP_016872165]
13) '9606.ENSP00000245787':
INSIG2 - Insulin-induced gene 2 protein; Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
[a.k.a. INSIG2-203, AAN28333.1, Q9Y5U4]
14) '9606.ENSP00000238892':
CRIPT - Cysteine-rich PDZ-binding protein; Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses.
[a.k.a. CXXC repeat containing interactor of PDZ3 domain, Q9P021, NP_054890]
15) '9606.ENSP00000344937':
DPY19L3 - Probable C-mannosyltransferase DPY19L3; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins; Belongs to the dpy-19 family.
[a.k.a. XR_935753.2, UPI0000070078, hsa:147991]
16) '9606.ENSP00000215941':
ANKRD54 - Ankyrin repeat domain-containing protein 54; Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.
[a.k.a. H7C3L3, ENST00000609454, ENSP00000393035]
17) '9606.ENSP00000379563':
TSPO - Translocator protein; Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism , but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral- type benzodiazepine receptor; can also bind isoquinoline carboxamides ; Belongs to the TspO/BZRP family.
[a.k.a. NM_000714, CAB011232, PBR]
18) '9606.ENSP00000347626':
NUDCD3 - NudC domain containing 3.
[a.k.a. NP_056147, NudCL, hsa:23386]
19) '9606.ENSP00000370803':
CCP110 - Centriolar coiled-coil protein of 110 kDa; Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and geno [...]
[a.k.a. NP_055526, R-HSA-69278, R-HSA-380320]
20) '9606.ENSP00000423600':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
101 query items
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