searching ... STRING: functional protein association networks

APOA2 - Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism; Belongs to the apolipoprotein A2 family. [a.k.a. R-HSA-388396, R-HSA-196854, NP_001634.1]

RTP3 - Receptor-transporting protein 3; Promotes functional cell surface expression of the bitter taste receptors TAS2R16 and TAS2R43; Belongs to the TMEM7 family. [a.k.a. R-HSA-388396, ENSG00000163825, R-HSA-162582]

CCL23 - C-C motif chemokine 23; Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. Belongs to the intercrine beta (chemokine CC) family. [a.k.a. uc002hks.3, CCL23-201, NM_005064.6]

ART4 - ADP-ribosyltransferase 4; Belongs to the Arg-specific ADP-ribosyltransferase family. [a.k.a. DO, ENSG00000111339, AY829431]

F9 - Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. Belongs to the peptidase S1 family. [a.k.a. ENST00000394090, J00136, R-HSA-140834]

GMPPA - Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. [a.k.a. ENST00000313597, 29926, ENST00000341142]

SLC38A2 - Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. [a.k.a. R-HSA-352230, 54407, ENST00000551374]

SLC13A1 - Solute carrier family 13 member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. [a.k.a. Q9BZW2, Solute carrier family 13 member 1, F8WEH1]

NOB1 - RNA-binding protein NOB1; May play a role in mRNA degradation (Probable). Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity); Belongs to the NOB1 family. [a.k.a. ENST00000561677, uc002exs.5, 6G53]

STARD10 - START domain-containing protein 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes. [a.k.a. ENSP00000440016, ENST00000544767, A0A024R5L8]

S100A14 - Protein S100-A14; Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium. [a.k.a. Q9HCY8, AF426828, ENSG00000189334]

RBKS - Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily. [a.k.a. uc002rlo.3, AC110084, 2.7.1.15]

PLGLB1 - Plasminogen-like protein B; May bind noncovalently to lysine binding sites present in the kringle structures of plasminogen. This may interfere with the binding of fibrin or alpha-2-antiplasmin to plasminogen and may result in the localization of activity at sites necessary for extracellular matrix destruction. [a.k.a. ENST00000355705.3, Q02325, PRGB]

RBP2 - Retinol-binding protein 2; Intracellular transport of retinol; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. [a.k.a. R-HSA-388396, Retinol-binding protein 2, R-HSA-196854]

VCAM1 - Vascular cell adhesion protein 1; Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha- 4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [a.k.a. NP_001069.1, NP_542413.1, ENST00000347652.6]

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