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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000440440':
ATF7IP - Activating transcription factor 7-interacting protein 1; Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Required for HUSH-mediated heterochromatin formation and gene silencing. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Stabilizes SETDB1, is required to stimulate histone methyltransferase activity of SETDB1 and facilitates the conversion of dimethylate [...]
[a.k.a. UPI000204AB35, ENST00000535179, XM_017019638.1]
2) '9606.ENSP00000362935':
ITGB1BP2 - Integrin beta-1-binding protein 2; May play a role during maturation and/or organization of muscles cells.
[a.k.a. BC108901, ITBP2_HUMAN, ENST00000373829]
3) '9606.ENSP00000440864':
NR4A1 - Nuclear receptor subfamily 4 group A member 1; Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury (By similarity). ECO:0000250|UniProtKB:P12813.
[a.k.a. 2QW4, R-HSA-9006925, NR4A1-206]
4) '9606.ENSP00000293441':
SHANK1 - SH3 and multiple ankyrin repeat domains protein 1; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction; Belongs to the SHANK family.
[a.k.a. ENSP00000351984, A8MXP5, ENST00000391814.5]
5) '9606.ENSP00000358310':
ITGA10 - Integrin alpha-10; Integrin alpha-10/beta-1 is a receptor for collagen; Belongs to the integrin alpha chain family.
[a.k.a. CCDS76204.1, XP_016858113, PRO827]
6) '9606.ENSP00000417583':
ST6GALNAC5 - Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Involved in the biosynthesis of ganglioside GD1a from GM1b. It exhibits higher activity with glycolipids than with glycoproteins (By similarity).
[a.k.a. CAD45372.1, EAX06386.1, ST6GalNAcV]
7) '9606.ENSP00000405424':
OXR1 - Oxidation resistance protein 1; May be involved in protection from oxidative damage.
[a.k.a. ENST00000517455.1, ENSP00000379172, BAC04711.1]
8) '9606.ENSP00000426638':
ETFDH - Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone; Belongs to the ETF-QO/FixC family.
[a.k.a. CCDS3800, CCDS64090.1, ENST00000510353]
9) '9606.ENSP00000371331':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000443598':
FAM214A - Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family.
[a.k.a. FAM214A-205, ENST00000570204.1, XP_005254604]
11) '9606.ENSP00000385957':
KBTBD12 - Kelch repeat and BTB domain containing 12.
[a.k.a. kelch repeat and BTB (POZ) domain containing 12, Q3ZCT8, NP_997218.2]
12) '9606.ENSP00000382767':
SEL1L3 - Protein sel-1 homolog 3; SEL1L family member 3.
[a.k.a. ENSP00000264868, SE1L3_HUMAN, KIAA0746]
13) '9606.ENSP00000453858':
PAK6 - Serine/threonine-protein kinase PAK 6; Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR- mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
[a.k.a. BUB1B-PAK6, ENSP00000452737, G5E9R2]
14) '9606.ENSP00000359240':
LZTS2 - Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. Belongs to the LZTS2 family.
[a.k.a. ENST00000311876, AAK31577.1, NM_001318100]
15) '9606.ENSP00000439281':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
16) '9606.ENSP00000262113':
MYOM2 - Myomesin-2; Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
[a.k.a. CAA48832.1, P54296, AAH52969.1]
17) '9606.ENSP00000259365':
TMOD1 - Tropomodulin-1; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
[a.k.a. uc004axk.3, NM_001166116, HPA051202]
18) '9606.ENSP00000264431':
RAPGEF2 - Rap guanine nucleotide exchange factor 2; Functions as a guanine nucleotide exchange factor (GEF), which activates Rap and Ras family of small GTPases by exchanging bound GDP for free GTP in a cAMP-dependent manner. Serves as a link between cell surface receptors and Rap/Ras GTPases in intracellular signaling cascades. Acts also as an effector for Rap1 by direct association with Rap1-GTP thereby leading to the amplification of Rap1-mediated signaling. Shows weak activity on HRAS. It is controversial whether RAPGEF2 binds cAMP and cGMP or not. Its binding to ligand-activated beta-1 adr [...]
[a.k.a. UPI0001D3B971, Rap guanine nucleotide exchange factor (GEF) 2, ENST00000264431.8]
19) '9606.ENSP00000347602':
ARID4A - AT-rich interactive domain-containing protein 4A; DNA-binding protein which modulates activity of several transcription factors including RB1 (retinoblastoma-associated protein) and AR (androgen receptor) (By similarity). May function as part of an mSin3A repressor complex. Has no intrinsic transcriptional activity (By similarity). Plays a role in the regulation of epigenetic modifications at the PWS/AS imprinting center near the SNRPN promoter, where it might function as part of a complex with RB1 and ARID4B (By similarity). Involved in spermatogenesis, together with ARID4B, where it [...]
[a.k.a. XM_017021564, ENST00000348476, OMIM:180201]
20) '9606.ENSP00000334941':
PTPRU - Receptor-type tyrosine-protein phosphatase U; Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis; Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
[a.k.a. ENST00000323839, ENSP00000078545, hPTP-J]
101 query items
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