searching ... STRING: functional protein association networks

Version:
12.0

The following proteins in Homo sapiens appear to match your input.
Please review the list, then click 'Continue' to proceed.

<- Back ⤓ Mapping Continue ->

97 query items

showing page 1 of 5 • first • previous • next • last

1) '9606.ENSP00000445440':

PHKG1 - Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity). [a.k.a. AF254251, NR_047689, NM_006213]

2) '9606.ENSP00000393324':

EIF4E3 - Eukaryotic translation initiation factor 4E type 3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity (By similarity). [a.k.a. Q6NUT1, Q8N5X7, CCDS33786]

3) '9606.ENSP00000427114':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000338927':

ZNF385A - Zinc finger protein 385A; RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, binds the 3'- UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind CCNB1 mRNA. Alternatively, may also regulate p [...] [a.k.a. ENSP00000338927, ENSP00000447162, uc001sfy.4]

5) '9606.ENSP00000245903':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000302543':

CXXC5 - CXXC-type zinc finger protein 5; May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen). May repress COX4I2 transactivation induced by CHCHD2 and [...] [a.k.a. NM_001317200.2, CCDS43370.1, NP_001304137.1]

7) '9606.ENSP00000421725':

GC - Vitamin D-binding protein; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. Belongs to the ALB/AFP/VDB family. [a.k.a. NP_001191235, GC-206, ENST00000504199]

8) '9606.ENSP00000373918':

GARS1 - Glycine--tRNA ligase; Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis. Belongs to the class-II aminoacyl-tRNA synthetase family. [a.k.a. R-HSA-379716, 2ZT7, ENST00000389266]

9) '9606.ENSP00000474823':

RNF103-CHMP3 - RNF103-CHMP3 readthrough. [a.k.a. RNF103-CHMP3-201, ENSG00000249884, NM_001198954.1]

10) '9606.ENSP00000420914':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000359505':

SDHAF4 - Succinate dehydrogenase assembly factor 4, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Binds to the flavoprotein subunit SDHA in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron [...] [a.k.a. ENST00000370474, BC018085, Sdh8]

12) '9606.ENSP00000358283':

UFL1 - E3 UFM1-protein ligase 1; E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, a post-translational modification on lysine residues of proteins that may play a crucial role in a number of cellular processes. Mediates DDRGK1 ufmylation and may regulate the proteasomal degradation of DDRGK1 and CDK5RAP3 thereby modulating NF-kappa-B signaling. May also play a role in nuclear receptor-mediated transcription through TRIP4 ufmylation. May play a role in the unfolded protein response, mediating the ufmylation of multip [...] [a.k.a. Regulator of C53/LZAP and DDRGK1, NLBP, C0H5X5]

13) '9606.ENSP00000221480':

PEX11G - Peroxisomal membrane protein 11C; Promotes membrane protrusion and elongation on the peroxisomal surface; Belongs to the peroxin-11 family. [a.k.a. XP_011526730, BC008780, NM_001270539.1]

14) '9606.ENSP00000219611':

CAPN15 - Calpain-15; Calpain 15; Belongs to the peptidase C2 family. [a.k.a. HGNC:11182, XP_016879085.1, ENST00000219611]

15) '9606.ENSP00000387435':

ARTN - Artemin; Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. [a.k.a. EAX07079.1, R-HSA-162582, 2GYR]

16) '9606.ENSP00000395461':

BTBD19 - BTB/POZ domain-containing protein 19; BTB domain containing 19. [a.k.a. NP_001130009.1, XP_006710449, NM_001136537]

17) '9606.ENSP00000426568':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000322270':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

19) '9606.ENSP00000297785':

ALDH1A1 - Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo. [a.k.a. 4WB9, M31986, 216]

20) '9606.ENSP00000246112':

TLE6 - Transducin-like enhancer protein 6; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions; Belongs to the WD repeat Groucho/TLE family. [a.k.a. TLE6-210, NM_001143986, ENSP00000406893]

97 query items

showing page 1 of 5 • first • previous • next • last

<- Back ⤓ Mapping Continue ->

© STRING Consortium 2023

Credits

Access

Info

About