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The following proteins in
Homo sapiens
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38 query items
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1) '9606.ENSP00000447852':
POC1B-GALNT4 - Polypeptide N-acetylgalactosaminyltransferase; POC1B-GALNT4 readthrough.
[a.k.a. F8VUJ3, CCDS55860, ENST00000548729.5]
2) '9606.ENSP00000349877':
ATP13A1 - Manganese-transporting ATPase 13A1; Mediates manganese transport into the endoplasmic reticulum. The ATPase activity is required for cellular manganese homeostasis. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
[a.k.a. ENST00000497156, ENST00000357324, ATP13A1-207]
3) '9606.ENSP00000290691':
RGL4 - Ral-GDS-related protein; Ral guanine nucleotide dissociation stimulator like 4.
[a.k.a. RalGDS-like 4, NM_153615, ENSP00000480308]
4) '9606.ENSP00000337081':
ZNF112 - Zinc finger protein 112; May be involved in transcriptional regulation.
[a.k.a. AAF12816.1, zinc finger protein 112, ENSP00000253426]
5) '9606.ENSP00000305529':
SIRPG - Signal-regulatory protein gamma; Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen- specific T-cell proliferation and costimulates T-cell activation.
[a.k.a. CCDS13020.2, R-HSA-202733, AB042624]
6) '9606.ENSP00000221665':
FIZ1 - Flt3-interacting zinc finger protein 1; May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity).
[a.k.a. BC132777, XP_005259409, 84922]
7) '9606.ENSP00000386125':
ARMC5 - Armadillo repeat-containing protein 5; Involved in fetal development, T-cell function and adrenal gland growth homeostasis (By similarity). Negatively regulates adrenal cells survival. Plays a role in steroidogenesis, modulates steroidogenic enzymes expression and cortisol production.
[a.k.a. ENST00000563544, AK024430, ENSG00000140691]
8) '9606.ENSP00000352833':
PTPN22 - Tyrosine-protein phosphatase non-receptor type 22; Acts as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules. Associates with and probably dephosphorylates CBL. Dephosphorylates LCK at its activating 'Tyr-394' residue. Dephosphorylates ZAP70 at its activating 'Tyr-493' residue. Dephosphorylates the immune system activator SKAP2. Positively regulates toll-like receptor (TLR)-induced type 1 interferon production. Promotes host [...]
[a.k.a. PEST-domain phosphatase, NM_015967, XP_011539524]
9) '9606.ENSP00000265016':
BST1 - ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth; Belongs to the ADP-ribosyl cyclase family.
[a.k.a. R-HSA-196854, bone marrow stromal cell antigen 1, A6NC48]
10) '9606.ENSP00000435150':
KIAA0408 - Uncharacterized protein KIAA0408; KIAA0408.
[a.k.a. AB007868, ENST00000472335.2, OTTHUMG00000166439]
11) '9606.ENSP00000365261':
LST1 - Leukocyte-specific transcript 1 protein; Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
[a.k.a. ENSP00000365260, HGNC:14189, ENST00000396112.6]
12) '9606.ENSP00000219782':
MAZ - Myc-associated zinc finger protein; May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
[a.k.a. HPA065930, I3L4D3, UPI0000EE81B1]
13) '9606.ENSP00000346809':
PGAP1 - GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi (By similarity).
[a.k.a. ENST00000409475, ENST00000459896, AAX88854.1]
14) '9606.ENSP00000334246':
CYP4Z1 - Cytochrome P450 family 4 subfamily Z member 1.
[a.k.a. CYP4A20, ENST00000334194.3, 199974]
15) '9606.ENSP00000304908':
TXNDC2 - Thioredoxin domain-containing protein 2; Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.
[a.k.a. AAK94950.1, AF080095, HM005528]
16) '9606.ENSP00000269586':
ARL5C - Putative ADP-ribosylation factor-like protein 5C; Binds and exchanges GTP and GDP.
[a.k.a. URS00008B81CE, OTTHUMG00000179048, ENST00000581255.1]
17) '9606.ENSP00000339001':
TUBB - Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
[a.k.a. 203068, ENSP00000339001, R-HSA-69278]
18) '9606.ENSP00000380307':
JPH4 - Junctophilin-4; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity).
[a.k.a. ENSP00000322442, uc001wkq.3, JPHL1]
19) '9606.ENSP00000411816':
CSGALNACT1 - Chondroitin sulfate N-acetylgalactosaminyltransferase 1; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage formation and subsequent endochondral ossification. Moreover, is involved in the metabolism of aggrecan (By similarity).
[a.k.a. URS00008B7F38, NM_001354488.1, XP_006716423.1]
20) '9606.ENSP00000384359':
APOBEC3A - DNA dC->dU-editing enzyme APOBEC-3A; DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T- cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression thro [...]
[a.k.a. APOBEC3A_B, U03891, A3A]
38 query items
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