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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000457168':
SZT2 - KICSTOR complex protein SZT2; As part of the KICSTOR complex functions in the amino acid- sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by gluc [...]
[a.k.a. ENST00000310739, XR_001737075, chromosome 1 open reading frame 84]
2) '9606.ENSP00000345216':
USP54 - Inactive ubiquitin carboxyl-terminal hydrolase 54; Has no peptidase activity; Belongs to the peptidase C19 family.
[a.k.a. XP_011537670, XR_001747047, XR_001747038]
3) '9606.ENSP00000366093':
RORB - Nuclear receptor ROR-beta; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated p [...]
[a.k.a. 6096, Y08639, ENSP00000355068]
4) '9606.ENSP00000482345':
TBC1D3C - TBC1 domain family member 3C.
[a.k.a. XP_011523116, XM_006721904.2, XP_006721970.1]
5) '9606.ENSP00000359417':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000393097':
GABRA1 - Gamma-aminobutyric acid receptor subunit alpha-1; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel. The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By si [...]
[a.k.a. NM_001127645, GABRA1-219, ENSP00000430895]
7) '9606.ENSP00000358363':
PDE4DIP - Myomegalin; Functions as an anchor sequestering components of the cAMP- dependent pathway to Golgi and/or centrosomes (By similarity).
[a.k.a. XM_006711642, CR749273, ENSP00000436791]
8) '9606.ENSP00000267853':
MYZAP - Myocardial zonula adherens protein; Plays a role in cellular signaling via Rho-related GTP- binding proteins and subsequent activation of transcription factor SRF (By similarity). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity). Belongs to the MYZAP family.
[a.k.a. P0CAP1, HGNC:43444, Q8NC58]
9) '9606.ENSP00000235628':
NT5C1A - Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.
[a.k.a. Cytosolic 5'-nucleotidase IA, ENSG00000116981, ENSP00000235628]
10) '9606.ENSP00000312185':
ELMO1 - Engulfment and cell motility protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
[a.k.a. 2VSZ, ELMO1-208, XP_011513956]
11) '9606.ENSP00000364043':
SPIN2A - Spindlin-2A; May be involved in the regulation of cell cycle progression (By similarity). Exhibits H3K4me3-binding activity.
[a.k.a. ENST00000374906, XP_005262074.3, A0A024R9W1]
12) '9606.ENSP00000419952':
KCNAB1 - Voltage-gated potassium channel subunit beta-1; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its effect on the pore-forming alpha subunits (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the clos [...]
[a.k.a. ENST00000389633, AC125607, ENSP00000418048]
13) '9606.ENSP00000481762':
CSDE1 - Cold shock domain-containing protein E1; RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
[a.k.a. HPA018846, Q5TF05, ENSP00000432958]
14) '9606.ENSP00000418994':
SYNPR - Synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity); Belongs to the synaptophysin/synaptobrevin family.
[a.k.a. ENST00000460142, ENSP00000420383, SPO]
15) '9606.ENSP00000360214':
OPALIN - Opalin; Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
[a.k.a. B4DK96, AF367761, NM_001284320]
16) '9606.ENSP00000375894':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
17) '9606.ENSP00000299638':
POLR2M - DNA-directed RNA polymerase II subunit GRINL1A; Isoform 1 appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II). Pol II synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNA polymerase II transcription machinery. Isoform 1 may play a role in the Mediator complex-dependent regulation of transcription activation. Isoform 1 acts in vitro as a negative regulator of transcriptional activation; this repression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcr [...]
[a.k.a. NM_001018102.2, NM_015532.4, Q8NC58]
18) '9606.ENSP00000420095':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
19) '9606.ENSP00000309757':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
20) '9606.ENSP00000363092':
PRKG1 - cGMP-dependent protein kinase 1; Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins. Numerous protein targets for PRKG1 phosphorylation are implicated in modulating cellular calcium, but the contribution of each of these targets may vary substantially among cell types. Proteins that are phosphorylated by PRKG1 regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of the NO-s [...]
[a.k.a. NM_006258.4, R-HSA-162582, CCDS7244]
101 query items
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