searching ... STRING: functional protein association networks

Version:
12.0

The following proteins in Homo sapiens appear to match your input.
Please review the list, then click 'Continue' to proceed.

<- Back ⤓ Mapping Continue ->

101 query items

showing page 1 of 6 • first • previous • next • last

1) '9606.ENSP00000462355':

H4C15 - H4 clustered histone 15. [a.k.a. CH471087, AAH67496.1, R-HSA-5693565]

2) '9606.ENSP00000358404':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

3) '9606.ENSP00000367034':

H4C3 - H4 clustered histone 3. [a.k.a. CH471087, AAH67496.1, R-HSA-5693565]

4) '9606.ENSP00000352424':

TIAF1 - TGFB1-induced anti-apoptotic factor 1; Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation. [a.k.a. O95411, hsa:9220, NM_004740.3]

5) '9606.ENSP00000386207':

HMSD - Serpin-like protein HMSD; Putative serine protease inhibitor. [a.k.a. OTTHUMG00000060593, CCDS42441, OMIM:612086]

6) '9606.ENSP00000327533':

LYG2 - Lysozyme g-like protein 2; May act as a potent antibacterial protein that may play a role in the innate immunity; Belongs to the glycosyl hydrolase 23 family. [a.k.a. XM_017003751, EAX01873.1, LYG2-201]

7) '9606.ENSP00000354206':

ZNF219 - Zinc finger protein 219; Transcriptional regulator. Recognizes and binds 2 copies of the core DNA sequence motif 5'-GGGGG- 3'. Binds to the HMGN1 promoter and may repress HMGN1 expression. Regulates SNCA expression in primary cortical neurons. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with SOX9 (By similarity). Plays a role in chondrocyte differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. [a.k.a. ENSP00000388558, XP_005267796.1, ZNF219-210]

8) '9606.ENSP00000351539':

ZBTB18 - Zinc finger and BTB domain-containing protein 18; Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May [...] [a.k.a. XM_005273006, NP_991331.1, RP58]

9) '9606.ENSP00000420616':

TFDP2 - Transcription factor Dp-2; Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell- cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters. [a.k.a. R-HSA-170834, ENST00000317075, XM_017007091.1]

10) '9606.ENSP00000378769':

PPP1CB - Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] [a.k.a. R-HSA-170834, 3.1.3.16, ENST00000464273]

11) '9606.ENSP00000303540':

SCN1A - Sodium channel protein type 1 subunit alpha; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Plays a key role in brain, probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neurons induces pain without neurogenic inflammatio [...] [a.k.a. NM_001165963.3, NM_001353954.2, NM_001353951.2]

12) '9606.ENSP00000462667':

H4C14 - H4 clustered histone 14. [a.k.a. CH471087, AAH67496.1, R-HSA-5693565]

13) '9606.ENSP00000302895':

ARAP2 - Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase- activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity). [a.k.a. ENST00000511416.1, CENTD1, centaurin, delta 1]

14) '9606.ENSP00000323926':

TRPM8 - Transient receptor potential cation channel subfamily M member 8; Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of it [...] [a.k.a. R-HSA-3295583, XP_011510112, ENST00000409625.1]

15) '9606.ENSP00000454340':

MPV17L-2 - Mpv17-like protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. [a.k.a. MPV17L, H3BMD7, H3BMD7_HUMAN]

16) '9606.ENSP00000347168':

H4C11 - H4 clustered histone 11. [a.k.a. CH471087, AAH67496.1, R-HSA-5693565]

17) '9606.ENSP00000265440':

TFEC - Transcription factor EC; Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By sim [...] [a.k.a. CCDS5762, O14948, XP_011514271.1]

18) '9606.ENSP00000209718':

KRT23 - Keratin, type I cytoskeletal 23; Keratin 23. [a.k.a. ENST00000436344.7, ENST00000582754.5, KRT23-208]

19) '9606.ENSP00000265960':

MAPKAP1 - Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] [a.k.a. NM_001006617, SIN1, R-HSA-9006925]

20) '9606.ENSP00000389026':

CRISP3 - Cysteine rich secretory protein 3; Belongs to the CRISP family. [a.k.a. hsa:10321, UPI000020DE87, Aeg2]

101 query items

showing page 1 of 6 • first • previous • next • last

<- Back ⤓ Mapping Continue ->

© STRING Consortium 2023

Credits

Access

Info

About