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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000478671':
CNTNAP3B - Contactin-associated protein-like 3B; Contactin associated protein family member 3B; Belongs to the neurexin family.
[a.k.a. ENST00000491438, 728577, UPI0004620990]
2) '9606.ENSP00000277225':
ZNF462 - Zinc finger protein 462; Zinc finger nuclear factor involved in transcription by regulating chromatin structure and organization. Involved in the pluripotency and differentiation of embryonic stem cells by regulating SOX2, POU5F1/OCT4, and NANOG. By binding PBX1, prevents the heterodimerization of PBX1 and HOXA9 and their binding to DNA (By similarity). Regulates neuronal development and neural cell differentiation.
[a.k.a. XM_017014996, NP_067047.4, XP_016870485.1]
3) '9606.ENSP00000479207':
GALNTL5 - Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5; Probable inactive glycosyltransferase required during spermatid development. May participate in protein loading into the acrosomes and accumulation of ubiquitin-proteasome systems around the head-tail coupling apparatus region.
[a.k.a. NP_660335, ENST00000323731, XM_006715862.3]
4) '9606.ENSP00000401112':
SATB2 - DNA-binding protein SATB2; Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double- stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for th [...]
[a.k.a. NM_001172517.1, SATB family member 2, CAB067751]
5) '9606.ENSP00000483946':
PHF19 - PHD finger protein 19; Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem c [...]
[a.k.a. PHD finger protein 19, ENSP00000408479, UPI000006F815]
6) '9606.ENSP00000481878':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000389140':
DCC - Netrin receptor DCC; Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
[a.k.a. M32292, ENST00000579349.1, ENST00000582875]
8) '9606.ENSP00000358404':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000235382':
RGS2 - Regulator of G-protein signaling 2; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form. It is involved in the negative regulation of the angiotensin-activated signaling pathway. Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, the [...]
[a.k.a. R-HSA-388396, Cell growth-inhibiting gene 31 protein, R-HSA-162582]
10) '9606.ENSP00000388648':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
11) '9606.ENSP00000379065':
TRPS1 - Zinc finger transcription factor Trps1; Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.
[a.k.a. XM_011517266.2, ENST00000422939, KF495830]
12) '9606.ENSP00000310015':
ADAT1 - tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA-Ala.
[a.k.a. Q9BUB4, HGNC:228, ENST00000568510]
13) '9606.ENSP00000206423':
CCDC80 - Coiled-coil domain-containing protein 80; Promotes cell adhesion and matrix assembly.
[a.k.a. AY333429, NP_955805, SSG1]
14) '9606.ENSP00000304408':
COL3A1 - Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
[a.k.a. R-HSA-6806834, H7C435, R-HSA-8948216]
15) '9606.ENSP00000337838':
RTN4 - Reticulon-4; Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production. They influence nuclear envelope expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. However each isoform have specific functions mainly depending on their tissue expression specificities (Probable). [Isoform B]: Mainly function in endothelial cells and vascular smooth muscle cells, is also involved in immune system regulation (Probable). Modulator of vas [...]
[a.k.a. AAM64252.1, SP1507, C9J685]
16) '9606.ENSP00000312222':
ZHX3 - Zinc fingers and homeoboxes protein 3; Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA.
[a.k.a. ENST00000309060, XP_024307629, Zinc finger and homeodomain protein 3]
17) '9606.ENSP00000351530':
ZXDA - Zinc finger X-linked protein ZXDA; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
[a.k.a. P98168, ENSG00000198205, Zinc finger X-linked duplicated A]
18) '9606.ENSP00000337451':
EPHA3 - Ephrin type-A receptor 3; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in ca [...]
[a.k.a. 4TWO, AEE60977.1, NP_005224]
19) '9606.ENSP00000264463':
CDH10 - Cadherin-10; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
[a.k.a. NX_Q9Y6N8, ENST00000382239, 1008]
20) '9606.ENSP00000480824':
PKIB - cAMP-dependent protein kinase inhibitor beta; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains; Belongs to the PKI family.
[a.k.a. ENST00000258014, ENST00000368448.5, uc003pyz.4]
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