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The following proteins in
Homo sapiens
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88 query items
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1) '9606.ENSP00000482271':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
2) '9606.ENSP00000384490':
CBX6 - Chromobox protein homolog 6; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin. Recruitment to chromatin might occur in an H3K27me3- in [...]
[a.k.a. R-HSA-9006925, R-HSA-8943724, R-HSA-162582]
3) '9606.ENSP00000353670':
SPOCD1 - SPOC domain containing 1.
[a.k.a. ENST00000473361, URS0000EBC815, AK058077]
4) '9606.ENSP00000345629':
MAP3K15 - Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis.
[a.k.a. ENST00000333109, ENSG00000180815, ENSP00000428356]
5) '9606.ENSP00000295050':
SPRTN - SprT-like domain-containing protein Spartan; Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to [...]
[a.k.a. 6MDW, Q96BC5, R-HSA-110320]
6) '9606.ENSP00000290418':
CCDC142 - Coiled-coil domain containing 142.
[a.k.a. uc002slq.4, AK075209, ENST00000290418]
7) '9606.ENSP00000401197':
USP19 - Ubiquitin carboxyl-terminal hydrolase 19; Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiq [...]
[a.k.a. ENSG00000172046, BC142660, ENST00000306026]
8) '9606.ENSP00000480826':
H3C1 - H3 clustered histone 1.
[a.k.a. AAH96131.1, 5T0M, 2RI7]
9) '9606.ENSP00000276079':
NONO - Non-POU domain-containing octamer-binding protein; DNA- and RNA binding protein, involved in several nuclear processes. Binds the conventional octamer sequence in double-stranded DNA. Also binds single-stranded DNA and RNA at a site independent of the duplex site. Involved in pre-mRNA splicing, probably as a heterodimer with SFPQ. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. Together with PSPC1, required for the formation of nuclear paraspeckles. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclea [...]
[a.k.a. ENST00000454976.1, ENST00000471419, NonO protein]
10) '9606.ENSP00000273077':
PNKD - Probable hydrolase PNKD; Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa-B signaling pathway; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
[a.k.a. MR-1S, UPI00015B3BEE, AAH36457.1]
11) '9606.ENSP00000377699':
ADGRG4 - Adhesion G-protein coupled receptor G4; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
[a.k.a. NP_722576.3, NM_153834.4, NP_722576]
12) '9606.ENSP00000314029':
SENP3 - Sentrin-specific protease 3; Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148 [...]
[a.k.a. AAL25652.1, UPI000268AFEE, SENP3-208]
13) '9606.ENSP00000248450':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
14) '9606.ENSP00000357442':
PYGO2 - Pygopus homolog 2; Involved in signal transduction through the Wnt pathway.
[a.k.a. BC006132, ENSG00000163348, R-HSA-162582]
15) '9606.ENSP00000351926':
AP2A1 - AP-2 complex subunit alpha-1; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold [...]
[a.k.a. OTTHUMG00000183253, CCDS46148, ENST00000413690]
16) '9606.ENSP00000425759':
COX7C - Cytochrome c oxidase subunit 7C, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...]
[a.k.a. P15954, cytochrome c oxidase subunit VIIc, ENST00000511472]
17) '9606.ENSP00000384223':
ECE2-2 - EEF1AKMT4-ECE2 readthrough transcript protein; Converts big endothelin-1 to endothelin-1. May also have methyltransferase activity (By similarity). May play a role in amyloid- beta processing (By similarity); In the C-terminal section; belongs to the peptidase M13 family.
[a.k.a. ECE2, EEF1AKMT4-ECE2, hsa:110599583]
18) '9606.ENSP00000359240':
LZTS2 - Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. Belongs to the LZTS2 family.
[a.k.a. ENST00000311876, AAK31577.1, NM_001318100]
19) '9606.ENSP00000484658':
H3C3 - H3 clustered histone 3.
[a.k.a. AAH96131.1, 5T0M, 2RI7]
20) '9606.ENSP00000347672':
VANGL1 - VANGL planar cell polarity protein 1.
[a.k.a. ENST00000478369, STB2, VANGL1-203]
88 query items
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