node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
csgD | csgE | b1040 | b1039 | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | Curlin secretion specificity factor; May be involved in the biogenesis of curli organelles. | 0.999 |
csgD | csgF | b1040 | b1038 | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | Curli nucleation outer membrane protein; May be involved in the biogenesis of curli organelles. | 0.999 |
csgD | csgG | b1040 | b1037 | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | Curli production assembly/transport outer membrane lipoprotein; May be involved in the biogenesis of curli organelles. | 0.997 |
csgD | flhC | b1040 | b1891 | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | Flagellar class II regulon transcriptional activator, with FlhD; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways. | 0.539 |
csgD | flhD | b1040 | b1892 | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | Flagellar class II regulon transcriptional activator, with FlhC; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways. | 0.792 |
csgE | csgD | b1039 | b1040 | Curlin secretion specificity factor; May be involved in the biogenesis of curli organelles. | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | 0.999 |
csgE | csgF | b1039 | b1038 | Curlin secretion specificity factor; May be involved in the biogenesis of curli organelles. | Curli nucleation outer membrane protein; May be involved in the biogenesis of curli organelles. | 0.999 |
csgE | csgG | b1039 | b1037 | Curlin secretion specificity factor; May be involved in the biogenesis of curli organelles. | Curli production assembly/transport outer membrane lipoprotein; May be involved in the biogenesis of curli organelles. | 0.999 |
csgF | csgD | b1038 | b1040 | Curli nucleation outer membrane protein; May be involved in the biogenesis of curli organelles. | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | 0.999 |
csgF | csgE | b1038 | b1039 | Curli nucleation outer membrane protein; May be involved in the biogenesis of curli organelles. | Curlin secretion specificity factor; May be involved in the biogenesis of curli organelles. | 0.999 |
csgF | csgG | b1038 | b1037 | Curli nucleation outer membrane protein; May be involved in the biogenesis of curli organelles. | Curli production assembly/transport outer membrane lipoprotein; May be involved in the biogenesis of curli organelles. | 0.999 |
csgG | csgD | b1037 | b1040 | Curli production assembly/transport outer membrane lipoprotein; May be involved in the biogenesis of curli organelles. | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | 0.997 |
csgG | csgE | b1037 | b1039 | Curli production assembly/transport outer membrane lipoprotein; May be involved in the biogenesis of curli organelles. | Curlin secretion specificity factor; May be involved in the biogenesis of curli organelles. | 0.999 |
csgG | csgF | b1037 | b1038 | Curli production assembly/transport outer membrane lipoprotein; May be involved in the biogenesis of curli organelles. | Curli nucleation outer membrane protein; May be involved in the biogenesis of curli organelles. | 0.999 |
csgG | wza | b1037 | b2062 | Curli production assembly/transport outer membrane lipoprotein; May be involved in the biogenesis of curli organelles. | Colanic acid export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.587 |
flhC | csgD | b1891 | b1040 | Flagellar class II regulon transcriptional activator, with FlhD; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways. | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | 0.539 |
flhC | flhD | b1891 | b1892 | Flagellar class II regulon transcriptional activator, with FlhD; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways. | Flagellar class II regulon transcriptional activator, with FlhC; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways. | 0.999 |
flhD | csgD | b1892 | b1040 | Flagellar class II regulon transcriptional activator, with FlhC; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways. | csgBAC operon transcriptional regulator; The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae- expressing phenotype, up-regulates 10 genes and down-regulates 14 others. | 0.792 |
flhD | flhC | b1892 | b1891 | Flagellar class II regulon transcriptional activator, with FlhC; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways. | Flagellar class II regulon transcriptional activator, with FlhD; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways. | 0.999 |
wcaA | wcaB | b2059 | b2058 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative transferase; Protein involved in colanic acid biosynthetic process. | 0.992 |