STRINGSTRING
mglC mglC galS galS galT galT galE galE galM galM mglB mglB galK galK mglA mglA galP galP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mglCMethyl-galactoside transporter subunit; Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane. (336 aa)
galSGalactose- and fucose-inducible galactose regulon transcriptional isorepressor; Repressor of the mgl operon. Binds galactose and D-fucose as inducers. GalS binds to an operator DNA sequence within its own coding sequence (corresponding to residues 15 to 20). (346 aa)
galTGalactose-1-phosphate uridylyltransferase; Protein involved in cell surface antigen activity, host-interacting, galactose metabolic process, colanic acid biosynthetic process, carbohydrate catabolic process and response to desiccation; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (348 aa)
galEUDP-galactose-4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. It is only active on UDP-galactose and UDP-glucose. (338 aa)
galMAldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. (346 aa)
mglBMethyl-galactoside transporter subunit; This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor. (332 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). To a lesser extent, is also able to phosphorylate 2-deoxy-D-galactose and D- galactosamine. Is not able to use D-galacturonic acid, D-talose, L- altrose, and L-glucose as substrates. (382 aa)
mglAMethyl-galactoside ABC transporter ATPase; Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable). (506 aa)
galPD-galactose transporter; Uptake of galactose across the boundary membrane with the concomitant transport of protons into the cell (symport system); Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (464 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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