node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
citA | citB | b0619 | b0620 | Sensory histidine kinase in two-component regulatory system with CitB; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Functions as a sensor kinase that phosphorylates DpiA in the presence of citrate. | Response regulator in two-component regulatory system with CitA; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Regulates the transcription of citCDEFXGT, dpiAB, mdh and exuT. Binds specifically to the dpiB-citC intergenic region. | 0.999 |
citA | dctA | b0619 | b3528 | Sensory histidine kinase in two-component regulatory system with CitB; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Functions as a sensor kinase that phosphorylates DpiA in the presence of citrate. | C4-dicarboxylic acid, orotate and citrate transporter; Responsible for the aerobic transport of the dicarboxylates fumarate, L- and D-malate and to a lesser extent succinate, from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.641 |
citA | dcuB | b0619 | b4123 | Sensory histidine kinase in two-component regulatory system with CitB; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Functions as a sensor kinase that phosphorylates DpiA in the presence of citrate. | C4-dicarboxylate transporter, anaerobic; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.787 |
citB | citA | b0620 | b0619 | Response regulator in two-component regulatory system with CitA; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Regulates the transcription of citCDEFXGT, dpiAB, mdh and exuT. Binds specifically to the dpiB-citC intergenic region. | Sensory histidine kinase in two-component regulatory system with CitB; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Functions as a sensor kinase that phosphorylates DpiA in the presence of citrate. | 0.999 |
citB | dcuB | b0620 | b4123 | Response regulator in two-component regulatory system with CitA; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Regulates the transcription of citCDEFXGT, dpiAB, mdh and exuT. Binds specifically to the dpiB-citC intergenic region. | C4-dicarboxylate transporter, anaerobic; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.400 |
dctA | citA | b3528 | b0619 | C4-dicarboxylic acid, orotate and citrate transporter; Responsible for the aerobic transport of the dicarboxylates fumarate, L- and D-malate and to a lesser extent succinate, from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Sensory histidine kinase in two-component regulatory system with CitB; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Functions as a sensor kinase that phosphorylates DpiA in the presence of citrate. | 0.641 |
dctA | dcuB | b3528 | b4123 | C4-dicarboxylic acid, orotate and citrate transporter; Responsible for the aerobic transport of the dicarboxylates fumarate, L- and D-malate and to a lesser extent succinate, from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | C4-dicarboxylate transporter, anaerobic; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.913 |
dcuB | citA | b4123 | b0619 | C4-dicarboxylate transporter, anaerobic; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Sensory histidine kinase in two-component regulatory system with CitB; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Functions as a sensor kinase that phosphorylates DpiA in the presence of citrate. | 0.787 |
dcuB | citB | b4123 | b0620 | C4-dicarboxylate transporter, anaerobic; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Response regulator in two-component regulatory system with CitA; Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Regulates the transcription of citCDEFXGT, dpiAB, mdh and exuT. Binds specifically to the dpiB-citC intergenic region. | 0.400 |
dcuB | dctA | b4123 | b3528 | C4-dicarboxylate transporter, anaerobic; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | C4-dicarboxylic acid, orotate and citrate transporter; Responsible for the aerobic transport of the dicarboxylates fumarate, L- and D-malate and to a lesser extent succinate, from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.913 |
dcuB | fumB | b4123 | b4122 | C4-dicarboxylate transporter, anaerobic; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Anaerobic class I fumarate hydratase (fumarase B); Catalyzes the reversible hydration of fumarate to (S)-malate. Functions in the generation of fumarate for use as an anaerobic electron acceptor. To a lesser extent, also displays D-tartrate dehydratase activity, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Is required for anaerobic growth on D-tartrate. Belongs to the class-I fumarase family. | 0.984 |
fumB | dcuB | b4122 | b4123 | Anaerobic class I fumarate hydratase (fumarase B); Catalyzes the reversible hydration of fumarate to (S)-malate. Functions in the generation of fumarate for use as an anaerobic electron acceptor. To a lesser extent, also displays D-tartrate dehydratase activity, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Is required for anaerobic growth on D-tartrate. Belongs to the class-I fumarase family. | C4-dicarboxylate transporter, anaerobic; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.984 |