Organism Overview: Mycoplasma genitalium


 
dnaN protein networkhttps://string-db.org/network/243273.MG_001DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
MG_002 protein networkhttps://string-db.org/network/243273.MG_002DnaJ domain protein; Identified by similarity to EGAD:47211; match to protein family HMM PF00226.
gyrB protein networkhttps://string-db.org/network/243273.MG_003DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
gyrA protein networkhttps://string-db.org/network/243273.MG_004DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
serS protein networkhttps://string-db.org/network/243273.MG_005seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
tmk protein networkhttps://string-db.org/network/243273.MG_006Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
MG_007 protein networkhttps://string-db.org/network/243273.MG_007DNA polymerase III delta prime subunit, putative; Identified by similarity to EGAD:56824.
mnmE protein networkhttps://string-db.org/network/243273.MG_008tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
MG_009 protein networkhttps://string-db.org/network/243273.MG_009Deoxyribonuclease, TatD family, putative; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010.
MG_010 protein networkhttps://string-db.org/network/243273.MG_010DNA primase-related protein; Identified by similarity to EGAD:56796; match to protein family HMM PF01751; match to protein family HMM TIGR00646.
MG_011 protein networkhttps://string-db.org/network/243273.MG_011Conserved hypothetical protein; MG011 has a below trusted cutoff similarity to alpha-L-glutamate ligases, RimK family (TIGR00768). The adjacent gene, MG012, is a strong hit to that family; identi [...]
MG_012 protein networkhttps://string-db.org/network/243273.MG_012alpha-L-glutamate ligases, RimK family, putative; Identified by similarity to EGAD:56788; match to protein family HMM PF02222; match to protein family HMM TIGR00768; Belongs to the RimK family.
folD protein networkhttps://string-db.org/network/243273.MG_013Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysi [...]
MG_014 protein networkhttps://string-db.org/network/243273.MG_014ABC transporter, ATP-binding/permease protein; MG014 has 6 transmembrane regions plus an ATP binding domain; identified by similarity to EGAD:56782; match to protein family HMM PF00005; match to [...]
MG_015 protein networkhttps://string-db.org/network/243273.MG_015ABC transporter, ATP-binding/permease protein; MG015 has 5 transmembrane regions plus an ATP binding domain; identified by similarity to EGAD:56779; match to protein family HMM PF00005; match to [...]
MG_018 protein networkhttps://string-db.org/network/243273.MG_018Helicase SNF2 family, putative; Identified by similarity to EGAD:56776; match to protein family HMM PF00176; match to protein family HMM PF00270; match to protein family HMM PF00271; match to pro [...]
dnaJ protein networkhttps://string-db.org/network/243273.MG_019Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
pip protein networkhttps://string-db.org/network/243273.MG_020Proline iminopeptidase; Specifically catalyzes the removal of N-terminal proline residues from peptides.
metG protein networkhttps://string-db.org/network/243273.MG_021methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
rpoE protein networkhttps://string-db.org/network/243273.MG_022DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity [...]
fba protein networkhttps://string-db.org/network/243273.MG_023Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1 [...]
ychF protein networkhttps://string-db.org/network/243273.MG_024GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily [...]
MG_025 protein networkhttps://string-db.org/network/243273.MG_025Identified by similarity to EGAD:56752; match to protein family HMM PF00535; Belongs to the glycosyltransferase 2 family.
efp protein networkhttps://string-db.org/network/243273.MG_026Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functi [...]
nusB protein networkhttps://string-db.org/network/243273.MG_027MG027 was recently shown to encode a protein with structural similarity to NusB. Liu, J. et al. 2004 'A conserved hypothetical protein from Mycoplasma genitalium shows structural homology to nusb [...]
MG_028 protein networkhttps://string-db.org/network/243273.MG_028Conserved hypothetical protein; MG028 has 4 transmembrane regions; identified by similarity to EGAD:56743.
MG_029 protein networkhttps://string-db.org/network/243273.MG_029DJ-1/PfpI family protein; Identified by similarity to EGAD:56740; match to protein family HMM PF01965.
upp protein networkhttps://string-db.org/network/243273.MG_030Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
polC protein networkhttps://string-db.org/network/243273.MG_031DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
MG_032 protein networkhttps://string-db.org/network/243273.MG_032Conserved hypothetical protein; MG032 has a possible signal peptide; identified by similarity to EGAD:56729; match to protein family HMM PF03072; match to protein family HMM PF03086; Belongs to t [...]
glpF protein networkhttps://string-db.org/network/243273.MG_033Glycerol uptake facilitator; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (B [...]
tdk protein networkhttps://string-db.org/network/243273.MG_034Thymidine kinase; Identified by similarity to SP:Q03221; match to protein family HMM PF00265.
hisS protein networkhttps://string-db.org/network/243273.MG_035histidyl-tRNA synthetase; Identified by similarity to SP:P30053; match to protein family HMM PF00587; match to protein family HMM TIGR00442.
aspS protein networkhttps://string-db.org/network/243273.MG_036aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
MG_037 protein networkhttps://string-db.org/network/243273.MG_037Nicotinate phosphoribosyltransferase (NAPRTase) family; Identified by similarity to GB:AAP96260.1; match to protein family HMM PF04095; Belongs to the NAPRTase family.
glpK protein networkhttps://string-db.org/network/243273.MG_038Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
MG_039 protein networkhttps://string-db.org/network/243273.MG_039FAD-dependent glycerol-3-phosphate dehydrogenase, putative; Identified by similarity to GB:AAP56366.1; match to protein family HMM PF01266.
MG_040 protein networkhttps://string-db.org/network/243273.MG_040Lipoprotein, putative; Identified by similarity to EGAD:57299; match to protein family HMM PF02608.
ptsH protein networkhttps://string-db.org/network/243273.MG_041Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport syste [...]
potA protein networkhttps://string-db.org/network/243273.MG_042Spermidine/putrescine ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the [...]
potB protein networkhttps://string-db.org/network/243273.MG_043Spermidine/putrescine ABC transporter, permease protein, putative; Required for the activity of the bacterial transport system of putrescine and spermidine; Belongs to the binding-protein-depende [...]
potC protein networkhttps://string-db.org/network/243273.MG_044Spermidine/putrescine ABC transporter, permease protein, putative; Required for the activity of the bacterial transport system of putrescine and spermidine; Belongs to the binding-protein-depende [...]
MG_045 protein networkhttps://string-db.org/network/243273.MG_045Spermidine/putrescine ABC transporter, spermidine/putrescine binding protein, putative; MG045 is part of an ABC tranporter cassette for spermidine/putrescine transport that includes MG042, MG043, [...]
tsaD protein networkhttps://string-db.org/network/243273.MG_046Metalloendopeptidase, putative, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenin [...]
metK protein networkhttps://string-db.org/network/243273.MG_047S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet forma [...]
ffh protein networkhttps://string-db.org/network/243273.MG_048Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
deoD protein networkhttps://string-db.org/network/243273.MG_049Purine nucleoside phosphorylase; Identified by similarity to SP:P09743; match to protein family HMM PF01048; match to protein family HMM TIGR00107; Belongs to the PNP/UDP phosphorylase family.
deoC protein networkhttps://string-db.org/network/243273.MG_050Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB ald [...]
pdp protein networkhttps://string-db.org/network/243273.MG_051Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization [...]
cdd protein networkhttps://string-db.org/network/243273.MG_052Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
manB protein networkhttps://string-db.org/network/243273.MG_053Phosphoglucomutase/phosphomannomutase, putative; Identified by similarity to EGAD:56902; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02 [...]
nusG protein networkhttps://string-db.org/network/243273.MG_054Transcription antitermination protein NusG, putative; Participates in transcription elongation, termination and antitermination.
MG_055 protein networkhttps://string-db.org/network/243273.MG_055Preprotein translocase, SecE subunit; MG055 has 1 transmembrane region. The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); [...]
rsmI protein networkhttps://string-db.org/network/243273.MG_056Tetrapyrrole (corrin/porphyrin) methylase protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
rnmV protein networkhttps://string-db.org/network/243273.MG_057Small primase-like protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By [...]
prs protein networkhttps://string-db.org/network/243273.MG_058Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
smpB protein networkhttps://string-db.org/network/243273.MG_059SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
MG_060 protein networkhttps://string-db.org/network/243273.MG_060Glycosyl transferase, group 2 family protein; Identified by similarity to EGAD:56871; match to protein family HMM PF00535; Belongs to the glycosyltransferase 2 family.
MG_061 protein networkhttps://string-db.org/network/243273.MG_061Major Facilitator Superfamily (MFS) transporter. MG061 has 11 transmembrane regions; identified by similarity to EGAD:56861; match to protein family HMM PF07672.
fruA protein networkhttps://string-db.org/network/243273.MG_062PTS system, fructose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphory [...]
fruK protein networkhttps://string-db.org/network/243273.MG_0631-phosphofructokinase, putative; Identified by similarity to GB:AAF08321.1; match to protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family.
MG_064 protein networkhttps://string-db.org/network/243273.MG_064ABC transporter, permease protein, putative; MG064 and MG065 comprise a likely ABC transporter cassette. There is no likely substrate binding protein in the genome vicinity. MG064 has 8 transmemb [...]
MG_065 protein networkhttps://string-db.org/network/243273.MG_065ABC transporter, ATP-binding protein; MG064 and MG065 comprise a likely ABC transporter cassette. There is no likely substrate binding protein in the genome vicinity; identified by similarity to [...]
tkt protein networkhttps://string-db.org/network/243273.MG_066Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
MG_067 protein networkhttps://string-db.org/network/243273.MG_067Lipoprotein, putative; Identified by similarity to EGAD:56846; match to protein family HMM PF01727; match to protein family HMM PF01732.
MG_068 protein networkhttps://string-db.org/network/243273.MG_068Lipoprotein, putative; Identified by similarity to EGAD:56843; match to protein family HMM PF01727; match to protein family HMM PF01732.
ptsG protein networkhttps://string-db.org/network/243273.MG_069PTS system, glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphoryl [...]
rpsB protein networkhttps://string-db.org/network/243273.MG_070Ribosomal protein S2; Identified by similarity to SP:P21464; match to protein family HMM PF00318; match to protein family HMM TIGR01011; Belongs to the universal ribosomal protein uS2 family.
pacL protein networkhttps://string-db.org/network/243273.MG_071ATPase, P-type (transporting), HAD superfamily, subfamily IC; Could mediate calcium influx.
secA protein networkhttps://string-db.org/network/243273.MG_072Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
uvrB protein networkhttps://string-db.org/network/243273.MG_073Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for ab [...]
MG_074 protein networkhttps://string-db.org/network/243273.MG_074Conserved hypothetical protein; MG074 has 1 transmembrane region; identified by similarity to EGAD:57133.
MG_075 protein networkhttps://string-db.org/network/243273.MG_075116 kDa surface antigen; Identified by similarity to GP:2222735.
MG_076 protein networkhttps://string-db.org/network/243273.MG_076Conserved hypothetical protein; MG076 has 3 transmembrane regions; identified by similarity to EGAD:57123.
oppB protein networkhttps://string-db.org/network/243273.MG_077Oligopeptide ABC transporter, permease protein (OppB); Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across [...]
oppC protein networkhttps://string-db.org/network/243273.MG_078Oligopeptide ABC transporter, permease protein (OppC); Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across [...]
oppD protein networkhttps://string-db.org/network/243273.MG_079Oligopeptide ABC transporter, ATP-binding protein; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system (By s [...]
oppF protein networkhttps://string-db.org/network/243273.MG_080Oligopeptide ABC transporter, ATP-binding protein; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system (By s [...]
rplK protein networkhttps://string-db.org/network/243273.MG_081Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
rplA protein networkhttps://string-db.org/network/243273.MG_082Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
pth protein networkhttps://string-db.org/network/243273.MG_083peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
tilS protein networkhttps://string-db.org/network/243273.MG_084tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is [...]
hprK protein networkhttps://string-db.org/network/243273.MG_085HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dep [...]
lgt protein networkhttps://string-db.org/network/243273.MG_086Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
rpsL protein networkhttps://string-db.org/network/243273.MG_087Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
rpsG protein networkhttps://string-db.org/network/243273.MG_088Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interfac [...]
fusA protein networkhttps://string-db.org/network/243273.MG_089Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) [...]
rpsF protein networkhttps://string-db.org/network/243273.MG_090Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
ssb protein networkhttps://string-db.org/network/243273.MG_091Identified by similarity to EGAD:11594; match to protein family HMM PF00436.
rpsR protein networkhttps://string-db.org/network/243273.MG_092Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal p [...]
rplI protein networkhttps://string-db.org/network/243273.MG_093Ribosomal protein L9; Binds to the 23S rRNA.
dnaB protein networkhttps://string-db.org/network/243273.MG_094Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.
MG_095 protein networkhttps://string-db.org/network/243273.MG_095Lipoprotein, putative; Identified by similarity to EGAD:57278.
MG_096 protein networkhttps://string-db.org/network/243273.MG_096Conserved hypothetical protein; MG096 has 1 transmembrane region; identified by similarity to EGAD:57305; match to protein family HMM PF03072; match to protein family HMM PF03086; Belongs to the [...]
ung protein networkhttps://string-db.org/network/243273.MG_097uracil-DNA glycosylase, putative; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
MG_098 protein networkhttps://string-db.org/network/243273.MG_098glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit; MG098 is part of the GatABC aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase complex (MG098-MG099-MG100). The gatC region [...]
gatA protein networkhttps://string-db.org/network/243273.MG_099glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organi [...]
gatB protein networkhttps://string-db.org/network/243273.MG_100glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tR [...]
MG_101 protein networkhttps://string-db.org/network/243273.MG_101Conserved hypothetical protein; MG101 has some similarity to bacterial regulatory proteins of the gntR family; identified by similarity to EGAD:57268.
trxB protein networkhttps://string-db.org/network/243273.MG_102Thioredoxin-disulfide reductase; Identified by similarity to SP:P75531; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
whiA protein networkhttps://string-db.org/network/243273.MG_103Conserved hypothetical protein; Involved in cell division and chromosome segregation.
rnr protein networkhttps://string-db.org/network/243273.MG_104Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
dacB protein networkhttps://string-db.org/network/243273.MG_105Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
def protein networkhttps://string-db.org/network/243273.MG_106Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
gmk protein networkhttps://string-db.org/network/243273.MG_107Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
MG_108 protein networkhttps://string-db.org/network/243273.MG_108Protein phosphatase 2C, putative; Identified by similarity to EGAD:57254; match to protein family HMM PF00481.
MG_109 protein networkhttps://string-db.org/network/243273.MG_109Serine/threonine protein kinase, putative; MG109 has 1 transmembrane region; identified by similarity to GB:AAL58474.1; match to protein family HMM PF00069; Belongs to the protein kinase superfam [...]
rsgA protein networkhttps://string-db.org/network/243273.MG_110Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature sub [...]
pgi protein networkhttps://string-db.org/network/243273.MG_111Glucose-6-phosphate isomerase; MG111 has 1 transmembrane region; identified by similarity to SP:P81181; match to protein family HMM PF00342.
rpe protein networkhttps://string-db.org/network/243273.MG_112Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
asnS protein networkhttps://string-db.org/network/243273.MG_113asparaginyl-tRNA synthetase; Identified by similarity to EGAD:57244; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457.
pgsA protein networkhttps://string-db.org/network/243273.MG_114CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyl [...]
MG_115 protein networkhttps://string-db.org/network/243273.MG_115Competence/damage-inducible protein CinA domain protein; Identified by similarity to EGAD:31034; match to protein family HMM PF02464; match to protein family HMM TIGR00199; Belongs to the CinA fa [...]
MG_116 protein networkhttps://string-db.org/network/243273.MG_116Conserved hypothetical protein; Identified by similarity to EGAD:57240.
MG_117 protein networkhttps://string-db.org/network/243273.MG_117Conserved hypothetical protein; MG117 has some similarity to the superoxide dismutase (Mn/Fe family), C-terminal domain; identified by similarity to EGAD:57238.
galE protein networkhttps://string-db.org/network/243273.MG_118UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reductio [...]
MG_119 protein networkhttps://string-db.org/network/243273.MG_119ABC transporter, ATP-binding protein; Part of the ABC transporter complex involved in carbohydrates import. Probably responsible for energy coupling to the transport system (By similarity).
MG_120 protein networkhttps://string-db.org/network/243273.MG_120This is part of an ABC transporter cassette. The permeases (MG120 and MG121) are similar to branched chain amino acid transporters; however the ATP-binding protein is much more similar to a galac [...]
MG_121 protein networkhttps://string-db.org/network/243273.MG_121This is part of an ABC transporter cassette. The permeases (MG120 and MG121) are similar to branched chain amino acid transporters; however the ATP-binding protein is much more similar to a galac [...]
topA protein networkhttps://string-db.org/network/243273.MG_122DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
MG_123 protein networkhttps://string-db.org/network/243273.MG_123Conserved hypothetical protein; MG123 has 1 transmembrane region; identified by similarity to EGAD:57226.
trx protein networkhttps://string-db.org/network/243273.MG_124Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
MG_125 protein networkhttps://string-db.org/network/243273.MG_125Cof-like hydrolase, putative; Identified by similarity to EGAD:57222; match to protein family HMM PF00702; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484.
trpS protein networkhttps://string-db.org/network/243273.MG_126tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
MG_127 protein networkhttps://string-db.org/network/243273.MG_127Spx subfamily protein; MG127 is >40% identical and 68% similar to to the Bacillus subtilis Spx regulatory protein, which interferes with activator-stimulated transcription in bacteria by binding [...]
nadK protein networkhttps://string-db.org/network/243273.MG_128Inorganic polyphosphate/ATP-NAD kinase, probable; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically [...]
MG_129 protein networkhttps://string-db.org/network/243273.MG_129Conserved hypothetical protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming s [...]
rny protein networkhttps://string-db.org/network/243273.MG_130Uncharacterized domain HDIG; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
MG_132 protein networkhttps://string-db.org/network/243273.MG_132HIT domain protein; Identified by similarity to EGAD:57208; match to protein family HMM PF01230.
MG_133 protein networkhttps://string-db.org/network/243273.MG_133Membrane protein, putative; MG133 has 5 transmembrane regions; identified by similarity to EGAD:57206.
MG_134 protein networkhttps://string-db.org/network/243273.MG_134Conserved hypothetical protein; Identified by similarity to EGAD:57204; match to protein family HMM PF02575; match to protein family HMM TIGR00103.
MG_135 protein networkhttps://string-db.org/network/243273.MG_135Membrane protein, putative; MG135 has 7 transmembrane regions; identified by similarity to EGAD:57200.
lysS protein networkhttps://string-db.org/network/243273.MG_136lysyl-tRNA synthetase; Identified by similarity to SP:P37477; match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class [...]
glf protein networkhttps://string-db.org/network/243273.MG_137UDP-galactopyranose mutase; Involved in the conversion of UDP-GalP into UDP-GalF through a 2-keto intermediate.
lepA protein networkhttps://string-db.org/network/243273.MG_138GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
rnj protein networkhttps://string-db.org/network/243273.MG_139Metallo-beta-lactamase superfamily protein; An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/ [...]
MG_140 protein networkhttps://string-db.org/network/243273.MG_140Conserved hypothetical protein; Identified by similarity to EGAD:57280; Belongs to the DNA2/NAM7 helicase family.
nusA protein networkhttps://string-db.org/network/243273.MG_141Transcription termination factor NusA; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/243273.MG_142Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
rbfA protein networkhttps://string-db.org/network/243273.MG_143Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
MG_144 protein networkhttps://string-db.org/network/243273.MG_144Conserved hypothetical protein; MG144 has 3 transmembrane regions; identified by similarity to EGAD:57271.
ribF protein networkhttps://string-db.org/network/243273.MG_145Riboflavin biosynthesis protein RibF; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
MG_146 protein networkhttps://string-db.org/network/243273.MG_146Conserved hypothetical protein; MG146 has 4 transmembrane regioins and a CBS domain pair; identified by similarity to EGAD:57267; match to protein family HMM PF00571; match to protein family HMM [...]
MG_147 protein networkhttps://string-db.org/network/243273.MG_147Membrane protein, putative; MG147 has 7 transmembrane regions; identified by similarity to EGAD:57265.
MG_148 protein networkhttps://string-db.org/network/243273.MG_148Conserved hypothetical protein; Identified by similarity to EGAD:57263.
MG_149 protein networkhttps://string-db.org/network/243273.MG_149Lipoprotein, putative; Identified by similarity to EGAD:57261.
rpsJ protein networkhttps://string-db.org/network/243273.MG_150Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/243273.MG_151Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosom [...]
rplD protein networkhttps://string-db.org/network/243273.MG_152Ribosomal protein L4/L1 family; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It [...]
rplW protein networkhttps://string-db.org/network/243273.MG_153Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking [...]
rplB protein networkhttps://string-db.org/network/243273.MG_154Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has [...]
rpsS protein networkhttps://string-db.org/network/243273.MG_155Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/243273.MG_156Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S as [...]
rpsC protein networkhttps://string-db.org/network/243273.MG_157Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/243273.MG_158Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/243273.MG_159Ribosomal protein L29; Identified by similarity to SP:P04457; match to protein family HMM PF00831; match to protein family HMM TIGR00012; Belongs to the universal ribosomal protein uL29 family.
rpsQ protein networkhttps://string-db.org/network/243273.MG_160Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/243273.MG_161Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/243273.MG_162Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplE protein networkhttps://string-db.org/network/243273.MG_163Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In [...]
rpsN protein networkhttps://string-db.org/network/243273.MG_164Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
rpsH protein networkhttps://string-db.org/network/243273.MG_165Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the [...]
rplF protein networkhttps://string-db.org/network/243273.MG_166Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA [...]
rplR protein networkhttps://string-db.org/network/243273.MG_167Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
rpsE protein networkhttps://string-db.org/network/243273.MG_168Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
rplO protein networkhttps://string-db.org/network/243273.MG_169Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/243273.MG_170Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at [...]
adk protein networkhttps://string-db.org/network/243273.MG_171Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
map protein networkhttps://string-db.org/network/243273.MG_172Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and [...]
infA protein networkhttps://string-db.org/network/243273.MG_173Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
rpmJ protein networkhttps://string-db.org/network/243273.MG_174Ribosomal protein L36; Identified by similarity to SP:P21194; match to protein family HMM PF00444; match to protein family HMM TIGR01022; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/243273.MG_175Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of [...]
rpsK protein networkhttps://string-db.org/network/243273.MG_176Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome.
rpoA protein networkhttps://string-db.org/network/243273.MG_177DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/243273.MG_178Ribosomal protein L17; Identified by similarity to EGAD:41362; match to protein family HMM PF01196; match to protein family HMM TIGR00059.
ecfA1 protein networkhttps://string-db.org/network/243273.MG_179Metal ion ABC transporter, ATP-binding protein, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF tran [...]
ecfA2 protein networkhttps://string-db.org/network/243273.MG_180Metal ion ABC transporter ATP-binding protein, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF trans [...]
MG_181 protein networkhttps://string-db.org/network/243273.MG_181Metal ion ABC transporter, permease protein; MG181 in part of a likely ABC trasporter cassette comprised of ATPases MG179 and MG180, plus this permaease. There is no likely substrate binding prot [...]
truA protein networkhttps://string-db.org/network/243273.MG_182tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
pepF protein networkhttps://string-db.org/network/243273.MG_183Identified by similarity to SP:Q53778; match to protein family HMM PF01432; match to protein family HMM TIGR00181.
MG_184 protein networkhttps://string-db.org/network/243273.MG_184Adenine-specific DNA modification methylase; MG184 is a N4/N6-methyltransferase family protein; identified by similarity to SP:P00472.
MG_185 protein networkhttps://string-db.org/network/243273.MG_185Lipoprotein, putative; Identified by similarity to EGAD:36928; match to protein family HMM PF03202; match to protein family HMM PF03305.
MG_186 protein networkhttps://string-db.org/network/243273.MG_186Lipoprotein MG186 has significant similarity to Staphylococcal nucleases (such as micrococcal nuclease); identified by similarity to EGAD:57300; match to protein family HMM PF00565.
MG_187 protein networkhttps://string-db.org/network/243273.MG_187ABC transporter, ATP-binding protein; MG187 is part of an ABC transporter cassette comprised of MG187, permeases MG188, and MG189; identified by similarity to EGAD:57298; match to protein family [...]
MG_188 protein networkhttps://string-db.org/network/243273.MG_188ABC transporter, permease protein; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the b [...]
MG_189 protein networkhttps://string-db.org/network/243273.MG_189ABC transporter, permease protein; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.
nrnA protein networkhttps://string-db.org/network/243273.MG_190Phosphoesterase, DHH subfamily 1; Bifunctional enzyme which has both oligoribonuclease and pAp- phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and sh [...]
mgpA protein networkhttps://string-db.org/network/243273.MG_191MgPa adhesin; The protein is the major adhesin mediating the attachment of this mycoplasma to the ciliated epithelium.
p110 protein networkhttps://string-db.org/network/243273.MG_192MG192 encodes protein P110. It is part of a cytadherence related operon including genes MG190 to MG192 (PMID: 14659545). This gene has also been called mgpC and Mgp-operon protein 3. MG192 has 2 [...]
pheS protein networkhttps://string-db.org/network/243273.MG_194phenylalanyl-tRNA synthetase, alpha subunit; Identified by similarity to SP:P17921; match to protein family HMM PF01409; match to protein family HMM TIGR00468; Belongs to the class-II aminoacyl-t [...]
pheT protein networkhttps://string-db.org/network/243273.MG_195phenylalanyl-tRNA synthetase, beta subunit; Identified by similarity to EGAD:56761; match to protein family HMM PF01588; match to protein family HMM PF03483; match to protein family HMM PF03484; [...]
infC protein networkhttps://string-db.org/network/243273.MG_196Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/243273.MG_197Ribosomal protein L35; Identified by similarity to SP:P55874; match to protein family HMM PF01632; match to protein family HMM TIGR00001; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/243273.MG_198Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing function [...]
MG_200 protein networkhttps://string-db.org/network/243273.MG_200DnaJ domain protein; Identified by similarity to EGAD:56725; match to protein family HMM PF00226.
grpE protein networkhttps://string-db.org/network/243273.MG_201Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nu [...]
MG_202 protein networkhttps://string-db.org/network/243273.MG_202Conserved hypothetical protein; Identified by similarity to EGAD:56721.
parE protein networkhttps://string-db.org/network/243273.MG_203DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circul [...]
parC protein networkhttps://string-db.org/network/243273.MG_204DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circul [...]
hrcA protein networkhttps://string-db.org/network/243273.MG_205Heat-inducible transcription repressor HrcA, putative; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
uvrC protein networkhttps://string-db.org/network/243273.MG_206Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsi [...]
MG_207 protein networkhttps://string-db.org/network/243273.MG_207Identified by similarity to EGAD:57314; match to protein family HMM PF00149; match to protein family HMM TIGR00040; Belongs to the metallophosphoesterase superfamily. YfcE family.
MG_208 protein networkhttps://string-db.org/network/243273.MG_208Glycoprotease family protein; The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); identified by similarity to EGAD:57160; ma [...]
MG_209 protein networkhttps://string-db.org/network/243273.MG_209Pseudouridine synthase, RluA family; Identified by similarity to EGAD:57156; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005.
lspA protein networkhttps://string-db.org/network/243273.MG_210Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
MG_211 protein networkhttps://string-db.org/network/243273.MG_211Conserved hypothetical protein; Identified by similarity to EGAD:57137.
plsC protein networkhttps://string-db.org/network/243273.MG_2121-acyl-sn-glycerol-3-phosphate acyltransferase, putative; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position; Belongs to the 1-acyl-sn-glyc [...]
scpA protein networkhttps://string-db.org/network/243273.MG_213Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA awa [...]
scpB protein networkhttps://string-db.org/network/243273.MG_214Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA awa [...]
pfk protein networkhttps://string-db.org/network/243273.MG_2156-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase typ [...]
pyk protein networkhttps://string-db.org/network/243273.MG_216Pyruvate kinase; Identified by similarity to SP:Q02499; match to protein family HMM PF00224; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
MG_217 protein networkhttps://string-db.org/network/243273.MG_217The surface protein P65 is a constituent of the Mycoplasma pneumoniae cytoskeleton and is present at reduced levels in mutants lacking the cytadherence accessory protein HMW2; identified by simil [...]
hmw2 protein networkhttps://string-db.org/network/243273.MG_218HMW2 cytadherence accessory protein; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins cont [...]
MG_219 protein networkhttps://string-db.org/network/243273.MG_219Hypothetical protein; Identified by Glimmer2; putative.
MG_220 protein networkhttps://string-db.org/network/243273.MG_220Conserved hypothetical protein; MG220 has 1 transmembrane region; identified by similarity to EGAD:57057.
mraZ protein networkhttps://string-db.org/network/243273.MG_221mraZ protein; Identified by similarity to EGAD:57052; match to protein family HMM PF02381; match to protein family HMM TIGR00242.
rsmH protein networkhttps://string-db.org/network/243273.MG_222S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
MG_223 protein networkhttps://string-db.org/network/243273.MG_223Conserved hypothetical protein; Identified by similarity to EGAD:57046.
ftsZ protein networkhttps://string-db.org/network/243273.MG_224Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
MG_225 protein networkhttps://string-db.org/network/243273.MG_225MG225 is a member of the Amino Acid-Polyamine-Organocation (APC) family. MG225 has 12 transmembrane regions; identified by similarity to EGAD:57029; match to protein family HMM PF00324.
MG_226 protein networkhttps://string-db.org/network/243273.MG_226MG226 is a member of the Amino Acid-Polyamine-Organocation (APC) family; identified by similarity to EGAD:57024; match to protein family HMM PF00324; To M.genitalium MG225.
thyA protein networkhttps://string-db.org/network/243273.MG_227Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
dhfR protein networkhttps://string-db.org/network/243273.MG_228Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
nrdF protein networkhttps://string-db.org/network/243273.MG_229Ribonucleoside-diphosphate reductase, beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (B [...]
nrdI protein networkhttps://string-db.org/network/243273.MG_230nrdI protein; Probably involved in ribonucleotide reductase function.
nrdE protein networkhttps://string-db.org/network/243273.MG_231Ribonucleoside-diphosphate reductase, alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides ( [...]
rplU protein networkhttps://string-db.org/network/243273.MG_232Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
MG_233 protein networkhttps://string-db.org/network/243273.MG_233Conserved hypothetical protein; Identified by similarity to EGAD:56995; match to protein family HMM PF04327.
rpmA protein networkhttps://string-db.org/network/243273.MG_234Ribosomal protein L27; Identified by similarity to SP:P05657; match to protein family HMM PF01016; match to protein family HMM TIGR00062; Belongs to the bacterial ribosomal protein bL27 family.
nfo protein networkhttps://string-db.org/network/243273.MG_235Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal [...]
MG_236 protein networkhttps://string-db.org/network/243273.MG_236Expressed protein of unknown function; MG236 is similar to transcriptional regulators of the Fur family. The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. [...]
MG_237 protein networkhttps://string-db.org/network/243273.MG_237Conserved hypothetical protein; Identified by similarity to EGAD:56970.
tig protein networkhttps://string-db.org/network/243273.MG_238Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By simila [...]
lon protein networkhttps://string-db.org/network/243273.MG_239ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
MG_240 protein networkhttps://string-db.org/network/243273.MG_240Nicotinamide-nucleotide adenylyltransferase/conserved hypothetical protein; Identified by similarity to EGAD:56947; match to protein family HMM PF01467; match to protein family HMM PF01966; match [...]
MG_241 protein networkhttps://string-db.org/network/243273.MG_241Conserved hypothetical protein; MG241 has 2 transmembrane regions; identified by similarity to EGAD:57243.
MG_242 protein networkhttps://string-db.org/network/243273.MG_242Expressed protein of unknown function; MG242 has 2 transmembrane regions. The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)) [...]
uvrD protein networkhttps://string-db.org/network/243273.MG_244UvrD/REP helicase; Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-str [...]
MG_245 protein networkhttps://string-db.org/network/243273.MG_2455-formyltetrahydrofolate cyclo-ligase, putative; Involved in folate metabolism. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10- methenyltetrahydrofolate [...]
MG_246 protein networkhttps://string-db.org/network/243273.MG_246Identified by similarity to PDB:1T71_A; match to protein family HMM PF00149; match to protein family HMM TIGR00282.
plsY protein networkhttps://string-db.org/network/243273.MG_247Membrane protein, putative; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-p [...]
MG_248 protein networkhttps://string-db.org/network/243273.MG_248Conserved hypothetical protein; Identified by similarity to EGAD:57215; match to protein family HMM PF04816.
rpoD protein networkhttps://string-db.org/network/243273.MG_249RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the p [...]
dnaG protein networkhttps://string-db.org/network/243273.MG_250DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
glyS protein networkhttps://string-db.org/network/243273.MG_251glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
MG_252 protein networkhttps://string-db.org/network/243273.MG_252RNA methyltransferase, TrmH family, group 3; Identified by similarity to EGAD:57207; match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR0018 [...]
cysS protein networkhttps://string-db.org/network/243273.MG_253cysteinyl-tRNA synthetase; Identified by similarity to SP:Q06752; match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase fami [...]
ligA protein networkhttps://string-db.org/network/243273.MG_254DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as t [...]
MG_255 protein networkhttps://string-db.org/network/243273.MG_255Conserved hypothetical protein; MG255 has 3 transmsmbrane regions; identified by similarity to EGAD:57199.
MG_256 protein networkhttps://string-db.org/network/243273.MG_256Conserved hypothetical protein; MG256 has 3 transmembrane regions; identified by similarity to EGAD:57196.
rpmE protein networkhttps://string-db.org/network/243273.MG_257Ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
prfA protein networkhttps://string-db.org/network/243273.MG_258Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
MG_259 protein networkhttps://string-db.org/network/243273.MG_259Modification methylase, HemK family; Identified by similarity to EGAD:57189; match to protein family HMM PF02384; match to protein family HMM PF05175; match to protein family HMM TIGR00536.
MG_260 protein networkhttps://string-db.org/network/243273.MG_260Lipoprotein, putative; Identified by similarity to EGAD:57182; match to protein family HMM PF03202; match to protein family HMM PF03305.
polC-2 protein networkhttps://string-db.org/network/243273.MG_261DNA polymerase III, alpha subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exo [...]
polA protein networkhttps://string-db.org/network/243273.MG_2625'-3' exonuclease, putative; 5'-3' exonuclease acting preferentially on double-stranded DNA.
MG_263 protein networkhttps://string-db.org/network/243273.MG_263Cof-like hydrolase; Identified by similarity to EGAD:57126; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484.
coaE protein networkhttps://string-db.org/network/243273.MG_264dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
MG_265 protein networkhttps://string-db.org/network/243273.MG_265Cof-like hydrolase; Identified by similarity to EGAD:57116; match to protein family HMM PF00702; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484.
leuS protein networkhttps://string-db.org/network/243273.MG_266leucyl-tRNA synthetase; Identified by similarity to SP:P36430; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family.
MG_267 protein networkhttps://string-db.org/network/243273.MG_267Conserved hypothetical protein; MG267 has 2 transmembrane regions; identified by similarity to EGAD:57106.
MG_268 protein networkhttps://string-db.org/network/243273.MG_268Conserved hypothetical protein; MG268 is similar to deoxynucleoside kinase; however it is not similar enough to warrent such an annotation. This gene is not essential (Glass et al 1005 and Hutchi [...]
MG_269 protein networkhttps://string-db.org/network/243273.MG_269Conserved hypothetical protein; Identified by similarity to EGAD:57097.
lplA protein networkhttps://string-db.org/network/243273.MG_270Lipoyltransferase/lipoate-protein ligase, putative; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lip [...]
lpdA protein networkhttps://string-db.org/network/243273.MG_271Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
pdhC protein networkhttps://string-db.org/network/243273.MG_272Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic compone [...]
pdhB protein networkhttps://string-db.org/network/243273.MG_273Pyruvate dehydrogenase component E1, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three en [...]
pdhA protein networkhttps://string-db.org/network/243273.MG_274Pyruvate dehydrogenase component E1, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three e [...]
nox protein networkhttps://string-db.org/network/243273.MG_275NADH oxidase; Catalyzes the four-electron reduction of molecular oxygen to water; Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.
apt protein networkhttps://string-db.org/network/243273.MG_276Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
MG_277 protein networkhttps://string-db.org/network/243273.MG_277Membrane protein, putative; The orthologous gene in Mycoplasma pneumoniae was annotated as secretory protein gene secD. This was was based on psi-BLAST analysis and the authors commented the secD [...]
relA protein networkhttps://string-db.org/network/243273.MG_278GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to chan [...]
MG_279 protein networkhttps://string-db.org/network/243273.MG_279Expressed protein of unknown function; MG279 has 2 transmembrane regions. The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)) [...]
MG_280 protein networkhttps://string-db.org/network/243273.MG_280Conserved hypothetical protein; MG280 has 2 transmembrane regions; identified by similarity to EGAD:57038.
MG_281 protein networkhttps://string-db.org/network/243273.MG_281Conserved hypothetical protein; MG281 has 1 transmembrane region; identified by similarity to EGAD:57033.
greA protein networkhttps://string-db.org/network/243273.MG_282Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
proS protein networkhttps://string-db.org/network/243273.MG_283prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
MG_284 protein networkhttps://string-db.org/network/243273.MG_284Conserved hypothetical protein; Identified by similarity to EGAD:57018.
MG_285 protein networkhttps://string-db.org/network/243273.MG_285Conserved hypothetical protein; Identified by similarity to EGAD:57013.
MG_286 protein networkhttps://string-db.org/network/243273.MG_286Conserved hypothetical protein; MG286 has 1 transmembrane region; identified by similarity to EGAD:57008.
MG_287 protein networkhttps://string-db.org/network/243273.MG_287Acyl carrier protein, putative; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
p37 protein networkhttps://string-db.org/network/243273.MG_289Phosphonate ABC transporter, substrate binding protein (P37), putative; P37 is part of a high-affinity transport system.
p29 protein networkhttps://string-db.org/network/243273.MG_290Phosphonate ABC transporter, ATP-binding protein, putative; Part of a high-affinity transport system.
p69 protein networkhttps://string-db.org/network/243273.MG_291Phosphonate ABC transporter, permease protein (P69), putative; Probably part of a high-affinity transport system.
alaS protein networkhttps://string-db.org/network/243273.MG_292alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
MG_293 protein networkhttps://string-db.org/network/243273.MG_293Glycerophosphoryl diester phosphodiesterase family protein; MG293 and MG385 comprise a parrologous gene family. Both can be disrupted (Glass et al. 2005); identified by similarity to EGAD:56951; [...]
MG_294 protein networkhttps://string-db.org/network/243273.MG_294Major facilitator superfamily protein, putative; MG294 has 12 transmembrane regions; identified by similarity to EGAD:56948; match to protein family HMM PF07690; To E.coli YihN.
trmU protein networkhttps://string-db.org/network/243273.MG_295tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
MG_296 protein networkhttps://string-db.org/network/243273.MG_296Conserved hypothetical protein; Identified by similarity to EGAD:56931.
ftsY protein networkhttps://string-db.org/network/243273.MG_297Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the [...]
smc protein networkhttps://string-db.org/network/243273.MG_298Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
pta protein networkhttps://string-db.org/network/243273.MG_299Phosphate acetyltransferase; Identified by similarity to SP:P39646; match to protein family HMM PF01515; match to protein family HMM TIGR00651.
pgk protein networkhttps://string-db.org/network/243273.MG_300Phosphoglycerate kinase; Identified by similarity to SP:P36204; match to protein family HMM PF00162.
gap protein networkhttps://string-db.org/network/243273.MG_301Glyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first r [...]
MG_302 protein networkhttps://string-db.org/network/243273.MG_302Metal ion ABC transporter, permease protein, putative; MG302 is part of an ABC transporter cassette comprised of MG302-MG303-MG304. There is no predicted substrate binding protein in the vicinity [...]
MG_303 protein networkhttps://string-db.org/network/243273.MG_303Metal ion ABC transporter, ATP-binding protein, putative; MG303 is part of an ABC transporter cassette comprised of MG302-MG303-MG304. There is no predicted substrate binding protein in the vicin [...]
MG_304 protein networkhttps://string-db.org/network/243273.MG_304Metal ion ABC transporter, ATP binding protein, putative; MG304 is part of an ABC transporter cassette comprised of MG302-MG303-MG304. There is no predicted substrate binding protein in the vicin [...]
dnaK protein networkhttps://string-db.org/network/243273.MG_305Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
MG_306 protein networkhttps://string-db.org/network/243273.MG_306Membrane protein, putative; MG306 has 7 transmembrane regions; identified by similarity to EGAD:56882.
MG_307 protein networkhttps://string-db.org/network/243273.MG_307Lipoprotein, putative; Identified by similarity to EGAD:56878.
MG_308 protein networkhttps://string-db.org/network/243273.MG_308ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by similarity to EGAD:57201; match to protein family HMM PF00270; match to protein family HMM PF00271.
MG_309 protein networkhttps://string-db.org/network/243273.MG_309Lipoprotein, putative; MG309 is a lipoprotein with 1 transmembrane region; identified by similarity to EGAD:57195; Belongs to the MG307/MG309/MG338 family.
MG_310 protein networkhttps://string-db.org/network/243273.MG_310Hydrolase, alpha/beta fold family; MG310 belongs to the SwissProt lipase/esterase LIP3/bchO family; however the similarity to characterized lipase/esterases is weak, even with the Mycoplasma myco [...]
rpsD protein networkhttps://string-db.org/network/243273.MG_311Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
hmw1 protein networkhttps://string-db.org/network/243273.MG_312HMW1 cytadherence accessory protein; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins cont [...]
MG_313 protein networkhttps://string-db.org/network/243273.MG_313Membrane protein, putative; MG313 is part of the HMW1(MG312)-HMW3(MG317) gene cluster. The predicted protein has 7 transmembrane regions; identified by similarity to EGAD:36298.
MG_314 protein networkhttps://string-db.org/network/243273.MG_314Conserved hypothetical protein; MG314 has 4 transmembrane regions; identified by similarity to EGAD:36297.
MG_315 protein networkhttps://string-db.org/network/243273.MG_315DNA polymerase III, delta subunit, putative; Identified by similarity to EGAD:36296; match to protein family HMM PF06144.
MG_316 protein networkhttps://string-db.org/network/243273.MG_316ComEC/Rec2-related protein; MG316 has 9 transmembrane regions; identified by similarity to EGAD:36295; match to protein family HMM PF03772; match to protein family HMM TIGR00360.
hmw3 protein networkhttps://string-db.org/network/243273.MG_317HMW3 cytadherence accessory protein; Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins cont [...]
p32 protein networkhttps://string-db.org/network/243273.MG_318P32 adhesin; Adhesin necessary for successful cytadherence and virulence.
MG_319 protein networkhttps://string-db.org/network/243273.MG_319Conserved hypothetical protein; MG319 has 2 transmembrane regions; identified by similarity to EGAD:57176.
MG_320 protein networkhttps://string-db.org/network/243273.MG_320Membrane protein, putative; MG320 has 7 transmembrane regions; identified by similarity to EGAD:57173.
MG_321 protein networkhttps://string-db.org/network/243273.MG_321Lipoprotein, putative; Identified by similarity to EGAD:57170.
MG_322 protein networkhttps://string-db.org/network/243273.MG_322Potassium uptake protein, TrkH family, putative; The adjacent gene, MG323, is a likely TrkA accessory protein for this gene which has some similarity to TrkH potassium transporters. MG322 has 9 t [...]
MG_323 protein networkhttps://string-db.org/network/243273.MG_323Potassium uptake protein, TrkA family; MG322, the adjacent gene, which is on the opposite strand encodes a trk potassium uptake protein. MG323 is a likely accessory protein; identified by similar [...]
pepP protein networkhttps://string-db.org/network/243273.MG_324Metallopeptidase family M24 aminopeptidase; Identified by similarity to GB:AAN81374.1; match to protein family HMM PF00557; Belongs to the peptidase M24B family.
rpmG protein networkhttps://string-db.org/network/243273.MG_325Ribosomal protein L33; Identified by similarity to EGAD:57100; match to protein family HMM PF00471; match to protein family HMM TIGR01023; Belongs to the bacterial ribosomal protein bL33 family.
MG_326 protein networkhttps://string-db.org/network/243273.MG_326degV family protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
MG_327 protein networkhttps://string-db.org/network/243273.MG_327Hydrolase, alpha/beta fold family; MG327 belongs to the SwissProt lipase/esterase LIP3/bchO family; however the similarity to characterized lipase/esterases is weak, even with the Mycoplasma myco [...]
MG_328 protein networkhttps://string-db.org/network/243273.MG_328Conserved hypothetical protein; MG328 has 5 M protein repeats. These short repeats are found in multiple copies in bacterial M proteins. The M proteins bind to IgA and are closely associated with [...]
engA protein networkhttps://string-db.org/network/243273.MG_329GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) G [...]
cmk protein networkhttps://string-db.org/network/243273.MG_330Cytidylate kinase; Identified by similarity to SP:P38493; match to protein family HMM PF02224; match to protein family HMM TIGR00017.
MG_331 protein networkhttps://string-db.org/network/243273.MG_331Conserved hypothetical protein; MG331 has 1 transmembrane protein; identified by similarity to EGAD:57070.
MG_332 protein networkhttps://string-db.org/network/243273.MG_332Expressed protein of unknown function; The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); identified by similarity to EGAD: [...]
valS protein networkhttps://string-db.org/network/243273.MG_334valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
engB protein networkhttps://string-db.org/network/243273.MG_335GTP-binding protein engB, putative; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. [...]
csd protein networkhttps://string-db.org/network/243273.MG_336Aminotransferase, class V; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
MG_337 protein networkhttps://string-db.org/network/243273.MG_337Conserved hypothetical protein; Identified by similarity to EGAD:57017.
MG_338 protein networkhttps://string-db.org/network/243273.MG_338Lipoprotein, putative; Identified by similarity to EGAD:57012; Belongs to the MG307/MG309/MG338 family.
recA protein networkhttps://string-db.org/network/243273.MG_339recA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybr [...]
rpoC protein networkhttps://string-db.org/network/243273.MG_340DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/243273.MG_341DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
MG_342 protein networkhttps://string-db.org/network/243273.MG_342NADPH-dependent FMN reductase domain protein; Identified by similarity to EGAD:56881.
MG_343 protein networkhttps://string-db.org/network/243273.MG_343Conserved hypothetical protein; Identified by similarity to EGAD:56877.
MG_344 protein networkhttps://string-db.org/network/243273.MG_344Hydrolase, alpha/beta fold family; MG344 belongs to the SwissProt lipase/esterase LIP3/bchO family; however the similarity to characterized lipase/esterases is weak, even with the Mycoplasma myco [...]
ileS protein networkhttps://string-db.org/network/243273.MG_345isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
MG_346 protein networkhttps://string-db.org/network/243273.MG_346RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA m [...]
trmB protein networkhttps://string-db.org/network/243273.MG_347tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
MG_349 protein networkhttps://string-db.org/network/243273.MG_349Conserved hypothetical protein; Identified by similarity to EGAD:56850.
MG_350 protein networkhttps://string-db.org/network/243273.MG_350Expressed protein of unknown function; The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); identified by similarity to EGAD: [...]
ppa protein networkhttps://string-db.org/network/243273.MG_351Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
recU protein networkhttps://string-db.org/network/243273.MG_352Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired stran [...]
MG_353 protein networkhttps://string-db.org/network/243273.MG_353DNA-binding protein HU, putative; Identified by similarity to GB:AAK52476.1.
MG_354 protein networkhttps://string-db.org/network/243273.MG_354Conserved hypothetical protein; MG354 has 1 transmembrane region; identified by similarity to EGAD:56836.
clpB protein networkhttps://string-db.org/network/243273.MG_355ATP-dependent Clp protease, ATPase subunit; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ an [...]
MG_356 protein networkhttps://string-db.org/network/243273.MG_356Choline/ethanolamine kinase, putative; Identified by similarity to EGAD:56833; match to protein family HMM PF01633; match to protein family HMM PF01636.
ackA protein networkhttps://string-db.org/network/243273.MG_357Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
ruvA protein networkhttps://string-db.org/network/243273.MG_358Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exch [...]
ruvB protein networkhttps://string-db.org/network/243273.MG_359Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand [...]
MG_360 protein networkhttps://string-db.org/network/243273.MG_360ImpB/MucB/SamB family protein are often involved in UV protection and DNA repair. MG360 is not essential for growth on SP-4 media (Glass et al., 2005); identified by similarity to EGAD:56810; mat [...]
rplJ protein networkhttps://string-db.org/network/243273.MG_361Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein [...]
rplL protein networkhttps://string-db.org/network/243273.MG_362Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacter [...]
rpmF protein networkhttps://string-db.org/network/243273.MG_363Ribosomal protein L32; Identified by similarity to SP:O34687; match to protein family HMM PF01783; match to protein family HMM TIGR01031; Belongs to the bacterial ribosomal protein bL32 family.
MG_364 protein networkhttps://string-db.org/network/243273.MG_364Expressed protein of unknown function; MG364 has 1 transmembrane region. The expression of this M. genitalium protein was reported in a proteome analysis (Eur. J. Biochem. 267, 1571-1582 (2000)); [...]
fmt protein networkhttps://string-db.org/network/243273.MG_365methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
MG_366 protein networkhttps://string-db.org/network/243273.MG_366Conserved hypothetical protein; Identified by similarity to EGAD:57141.
rnc protein networkhttps://string-db.org/network/243273.MG_367Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
plsX protein networkhttps://string-db.org/network/243273.MG_368Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fa [...]
MG_369 protein networkhttps://string-db.org/network/243273.MG_369The DAKS domain is the predicted phosphatase domain of the dihydroxyacetone kinase family; identified by similarity to EGAD:57129; match to protein family HMM PF02734.
MG_370 protein networkhttps://string-db.org/network/243273.MG_370Pseudouridine synthase, RluA family; MG370 is not essential for growth on SP-4 media (Hutchison, et al., 1999; Glass, et al., 2005); identified by similarity to EGAD:57124; match to protein famil [...]
MG_371 protein networkhttps://string-db.org/network/243273.MG_371DHH family protein; Identified by similarity to EGAD:57119; match to protein family HMM PF01368; match to protein family HMM PF02272; Belongs to the mgp1/MG371 family.
thiI protein networkhttps://string-db.org/network/243273.MG_372Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photos [...]
MG_373 protein networkhttps://string-db.org/network/243273.MG_373Conserved hypothetical protein; Identified by similarity to EGAD:57109.
MG_374 protein networkhttps://string-db.org/network/243273.MG_374Conserved hypothetical protein; Identified by similarity to EGAD:57104.
thrS protein networkhttps://string-db.org/network/243273.MG_375threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
MG_376 protein networkhttps://string-db.org/network/243273.MG_376Conserved hypothetical protein; Identified by similarity to EGAD:57091.
MG_377 protein networkhttps://string-db.org/network/243273.MG_377Conserved hypothetical protein; Identified by similarity to EGAD:57088.
argS protein networkhttps://string-db.org/network/243273.MG_378arginyl-tRNA synthetase; Identified by similarity to SP:P46906; match to protein family HMM PF00750; match to protein family HMM PF05746; match to protein family HMM TIGR00456.
gidA protein networkhttps://string-db.org/network/243273.MG_379Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...]
rsmG protein networkhttps://string-db.org/network/243273.MG_380Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
MG_381 protein networkhttps://string-db.org/network/243273.MG_381Conserved hypothetical protein; Identified by similarity to EGAD:57069.
udk protein networkhttps://string-db.org/network/243273.MG_382Uridine kinase; Identified by similarity to EGAD:57059; match to protein family HMM PF00485; match to protein family HMM TIGR00235.
nadE protein networkhttps://string-db.org/network/243273.MG_383NH(3)-dependent NAD+ synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
obg protein networkhttps://string-db.org/network/243273.MG_384GTPase1 Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in contr [...]
MG_385 protein networkhttps://string-db.org/network/243273.MG_385Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. MG293 and MG385 comprise a parrologous gene family. Both can be disrupted wh [...]
p200 protein networkhttps://string-db.org/network/243273.MG_386P200 protein; Could be an accessory structural component in cytadherence.
era protein networkhttps://string-db.org/network/243273.MG_387GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly als [...]
ybeY protein networkhttps://string-db.org/network/243273.MG_388Expressed protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA; Be [...]
MG_389 protein networkhttps://string-db.org/network/243273.MG_389Conserved hypothetical protein; MG389 has 1 transmembrane region; identified by similarity to EGAD:57010.
MG_390 protein networkhttps://string-db.org/network/243273.MG_390ABC transporter, ATP-binding/permease protein; MG390 has 4 transmembrane regions, plus and ATP binding domain, and a peptidase domain. There is no predicted substrate binding protein or other ABC [...]
pepA protein networkhttps://string-db.org/network/243273.MG_391Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides [...]
groL protein networkhttps://string-db.org/network/243273.MG_392Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.
groES protein networkhttps://string-db.org/network/243273.MG_393Chaperonin, 10 kDa (GroES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
glyA protein networkhttps://string-db.org/network/243273.MG_394Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
MG_395 protein networkhttps://string-db.org/network/243273.MG_395Lipoprotein, putative; Identified by similarity to EGAD:41340; match to protein family HMM PF01727; match to protein family HMM PF01732.
rpiB protein networkhttps://string-db.org/network/243273.MG_396Ribose 5-phosphate isomerase B; Catalyzes the interconversion of ribulose-5-P and ribose-5-P. Belongs to the LacAB/RpiB family.
MG_397 protein networkhttps://string-db.org/network/243273.MG_397Conserved hypothetical protein; MG397 has 1 transmembrane region; identified by similarity to EGAD:35551.
atpC protein networkhttps://string-db.org/network/243273.MG_398ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpD protein networkhttps://string-db.org/network/243273.MG_399ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase [...]
atpG protein networkhttps://string-db.org/network/243273.MG_400ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the f [...]
atpA protein networkhttps://string-db.org/network/243273.MG_401ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains fa [...]
atpH protein networkhttps://string-db.org/network/243273.MG_402ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the e [...]
atpF protein networkhttps://string-db.org/network/243273.MG_403ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extra [...]
atpE protein networkhttps://string-db.org/network/243273.MG_404ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extra [...]
atpB protein networkhttps://string-db.org/network/243273.MG_405ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
MG_406 protein networkhttps://string-db.org/network/243273.MG_406Conserved hypothetical protein; MG406 has 3 transmembrane regions; identified by similarity to EGAD:41329.
eno protein networkhttps://string-db.org/network/243273.MG_407Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
msrA protein networkhttps://string-db.org/network/243273.MG_408methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sul [...]
MG_409 protein networkhttps://string-db.org/network/243273.MG_409Phosphate transport system regulatory protein PhoU, putative; MG409 is part of a likely phosphate ABC transporter (pstSCAB-phoU) operon comprised of MG412-MG409. The expression of this M. genital [...]
pstB protein networkhttps://string-db.org/network/243273.MG_410Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the A [...]
pstA protein networkhttps://string-db.org/network/243273.MG_411Phosphate ABC transporter, permease protein PstA; Could be part of a binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across t [...]
MG_412 protein networkhttps://string-db.org/network/243273.MG_412Lipoprotein gene MG412 is part of a likely phosphate ABC transporter cassette that also includes MG410 and MG411. MG409 is a phoU regulator gene for this cassette. All three transporter genes wer [...]
MG_414 protein networkhttps://string-db.org/network/243273.MG_414Conserved hypothetical protein; Gene disruption mutants in MG414 have 16% faster doubling times than wild type M. genitalium (Glass et al. 2005). MG414 has 1 transmembrane region; identified by s [...]
rpsI protein networkhttps://string-db.org/network/243273.MG_417Ribosomal protein S9; Identified by similarity to SP:P21470; match to protein family HMM PF00380; Belongs to the universal ribosomal protein uS9 family.
rplM protein networkhttps://string-db.org/network/243273.MG_418Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of [...]
dnaX protein networkhttps://string-db.org/network/243273.MG_419DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' t [...]
uvrA protein networkhttps://string-db.org/network/243273.MG_421Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed o [...]
MG_422 protein networkhttps://string-db.org/network/243273.MG_422Conserved hypothetical protein; Identified by similarity to EGAD:56801.
MG_423 protein networkhttps://string-db.org/network/243273.MG_423Conserved hypothetical protein; Identified by similarity to EGAD:56797; match to protein family HMM TIGR00649.
rpsO protein networkhttps://string-db.org/network/243273.MG_424Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several [...]
MG_425 protein networkhttps://string-db.org/network/243273.MG_425ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by similarity to EGAD:56787; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF0 [...]
rpmB protein networkhttps://string-db.org/network/243273.MG_426Ribosomal protein L28; Identified by similarity to SP:P37807; match to protein family HMM PF00830; match to protein family HMM TIGR00009; Belongs to the bacterial ribosomal protein bL28 family.
MG_427 protein networkhttps://string-db.org/network/243273.MG_427OsmC-like protein; Reduces organic and inorganic peroxide substrates. Protects the cell against oxidative stress.
MG_428 protein networkhttps://string-db.org/network/243273.MG_428MG428, which has features of a LuxR bacterial regulatory protein, is not essential for growth in SP-4 (Glass, et al., 2005); identified by similarity to EGAD:56778.
ptsI protein networkhttps://string-db.org/network/243273.MG_429Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
gpmI protein networkhttps://string-db.org/network/243273.MG_4302,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase fa [...]
tpiA protein networkhttps://string-db.org/network/243273.MG_431Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
MG_432 protein networkhttps://string-db.org/network/243273.MG_432Membrane protein, putative; MG432 has 7 transmembrane regions; identified by similarity to EGAD:56766; match to protein family HMM PF02588.
tsf protein networkhttps://string-db.org/network/243273.MG_433Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis [...]
pyrH protein networkhttps://string-db.org/network/243273.MG_434Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/243273.MG_435Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
cdsA protein networkhttps://string-db.org/network/243273.MG_437Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family.
MG_438 protein networkhttps://string-db.org/network/243273.MG_438Type I restriction modification DNA specificity domain protein; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a b [...]
MG_439 protein networkhttps://string-db.org/network/243273.MG_439Lipoprotein, putative; Identified by similarity to EGAD:57031; match to protein family HMM PF00938.
MG_440 protein networkhttps://string-db.org/network/243273.MG_440Lipoprotein, putative; Identified by similarity to EGAD:57044; match to protein family HMM PF00938; Belongs to the MG439/MG440 family.
MG_441 protein networkhttps://string-db.org/network/243273.MG_441Conserved hypothetical protein; MG441 has 1 transmembrane region; identified by similarity to EGAD:57026.
rbgA protein networkhttps://string-db.org/network/243273.MG_442GTP-binding conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Binds to the 23S rRNA (By similarity). Belongs to the TRAFAC class Ylq [...]
MG_443 protein networkhttps://string-db.org/network/243273.MG_443Membrane protein, putative; MG443 has 6 transmembrane regions; identified by similarity to EGAD:56981; match to protein family HMM PF02588.
rplS protein networkhttps://string-db.org/network/243273.MG_444Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/243273.MG_445tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rpsP protein networkhttps://string-db.org/network/243273.MG_446Ribosomal protein S16; Identified by similarity to SP:P21474; match to protein family HMM PF00886; match to protein family HMM TIGR00002.
MG_447 protein networkhttps://string-db.org/network/243273.MG_447Membrane protein, putative; MG447 has 11 transmembrane regions. There is similarity to the MATE efflux family proteins; identified by similarity to EGAD:56962.
msrB protein networkhttps://string-db.org/network/243273.MG_448methionine-R-sulfoxide reductase; Identified by similarity to SP:P35593; match to protein family HMM PF01641; match to protein family HMM TIGR00357.
MG_450 protein networkhttps://string-db.org/network/243273.MG_450degV family protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
tuf protein networkhttps://string-db.org/network/243273.MG_451Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
MG_452 protein networkhttps://string-db.org/network/243273.MG_452Membrane protein, putative; MG452 has 6 transmembrane regions; identified by similarity to EGAD:56932; match to protein family HMM PF07667.
galU protein networkhttps://string-db.org/network/243273.MG_453UTP-glucose-1-phosphate uridylyltransferase; May play a role in stationary phase survival; Belongs to the UDPGP type 2 family.
MG_454 protein networkhttps://string-db.org/network/243273.MG_454OsmC-like protein; Identified by similarity to EGAD:56922; match to protein family HMM PF02566; Belongs to the OsmC/Ohr family.
tyrS protein networkhttps://string-db.org/network/243273.MG_455tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
ftsH protein networkhttps://string-db.org/network/243273.MG_457ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane [...]
hpt protein networkhttps://string-db.org/network/243273.MG_458Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:Q02522; match to protein family HMM PF00156; match to protein family HMM TIGR01203.
MG_459 protein networkhttps://string-db.org/network/243273.MG_459Conserved hypothetical protein; MG459 may encode a 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; however M. genitalium does not synthesize isoprenyl pyrophosphate via deoxyxylulose; ident [...]
ldh protein networkhttps://string-db.org/network/243273.MG_460L-lactate dehydrogenase/malate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
MG_461 protein networkhttps://string-db.org/network/243273.MG_461HD domain protein; Identified by similarity to EGAD:56887; match to protein family HMM PF01966.
gltX protein networkhttps://string-db.org/network/243273.MG_462glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
rsmA protein networkhttps://string-db.org/network/243273.MG_463Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
yidC protein networkhttps://string-db.org/network/243273.MG_464Membrane protein, putative; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins [...]
rnpA protein networkhttps://string-db.org/network/243273.MG_465Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
rpL34 protein networkhttps://string-db.org/network/243273.MG_466Ribosomal protein L34; Identified by similarity to SP:P02437; match to protein family HMM PF00468; match to protein family HMM TIGR01030; Belongs to the bacterial ribosomal protein bL34 family.
MG_467 protein networkhttps://string-db.org/network/243273.MG_467ABC transporter, ATP-binding protein; MG467 is part of an ABC transporter cassette comprised of MG467, permease MG468, and ATP binding protein MG468.1. There is no predicted substrate binding pro [...]
MG_468 protein networkhttps://string-db.org/network/243273.MG_468ABC transporter, permease protein; MG468 has 8 transmembrane regions. The gene is part of a likely ABC transporter cassette. The flanking genes are both ATPases. There is no evidence of a substra [...]
dnaA protein networkhttps://string-db.org/network/243273.MG_469Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
MG_470 protein networkhttps://string-db.org/network/243273.MG_470CobQ/CobB/MinD/ParA nucleotide binding domain; Identified by similarity to EGAD:47213; match to protein family HMM PF01656; Belongs to the ParA family.
rpmG-2 protein networkhttps://string-db.org/network/243273.MG_473Ribosomal protein L33 type 2; old_locus_tag=MG055.1; identified by similarity to SP:Q06798; match to protein family HMM TIGR01023; Belongs to the bacterial ribosomal protein bL33 family.
MG_474 protein networkhttps://string-db.org/network/243273.MG_474Conserved hypothetical protein; MG55.2 has 3 transmembrane regions. old_locus_tag=MG055.2; identified by similarity to EGAD:56892.
secG protein networkhttps://string-db.org/network/243273.MG_476Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family.
MG_477 protein networkhttps://string-db.org/network/243273.MG_477Conserved hypothetical protein; old_locus_tag=MG141.1; identified by similarity to GP:14247037; match to protein family HMM PF04296.
MG_478 protein networkhttps://string-db.org/network/243273.MG_478Conserved hypothetical protein; MG149.1 has 2 transmembrane regions. old_locus_tag=MG149.1; identified by similarity to EGAD:57259.
MG_480 protein networkhttps://string-db.org/network/243273.MG_480Conserved hypothetical protein; old_locus_tag=MG210.1; identified by similarity to EGAD:57145.
rpsU protein networkhttps://string-db.org/network/243273.MG_48130S ribosomal protein S21; old_locus_tag=MG210.2; identified by match to protein family HMM TIGR00030; Belongs to the bacterial ribosomal protein bS21 family.
acpS protein networkhttps://string-db.org/network/243273.MG_482Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
MG_491 protein networkhttps://string-db.org/network/243273.MG_491Conserved hypothetical protein; old_locus_tag=MG218.1; identified by similarity to EGAD:57067.
MG_494 protein networkhttps://string-db.org/network/243273.MG_494Conserved hypothetical protein; old_locus_tag=MG255.1; identified by similarity to EGAD:57199.
mutM protein networkhttps://string-db.org/network/243273.MG_498formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a [...]
MG_505 protein networkhttps://string-db.org/network/243273.MG_505Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
MG_515 protein networkhttps://string-db.org/network/243273.MG_515Conserved hypothetical protein; MG323.1 has 4 transmembrane proteins. old_locus_tag=MG323.1; identified by similarity to EGAD:57110.
MG_516 protein networkhttps://string-db.org/network/243273.MG_516Hypothetical protein; old_locus_tag=MG335.1; identified by Glimmer2; putative.
MG_517 protein networkhttps://string-db.org/network/243273.MG_517Glycosyl transferase, group 2 family protein; Processive glycosyltransferase involved in the biosynthesis of both the non-bilayer-prone beta-monoglycosyldiacylglycerol and the bilayer-forming mem [...]
MG_521 protein networkhttps://string-db.org/network/243273.MG_521Membrane protein, putative; MG350.1 has 5 transmembrane regions. old_locus_tag=MG350.1; identified by similarity to EGAD:56844.
rpsT protein networkhttps://string-db.org/network/243273.MG_522Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
MG_524 protein networkhttps://string-db.org/network/243273.MG_524Conserved hypothetical protein; MG384.1 has 3 transmembrane regions. old_locus_tag=MG384.1; identified by similarity to EGAD:57035.
MG_525 protein networkhttps://string-db.org/network/243273.MG_525Conserved hypothetical protein.
MG_526 protein networkhttps://string-db.org/network/243273.MG_526ABC transporter, ATP-binding protein; MG468.1 is part of an ABC transporter cassette comprised of ATP binding protein MG467, permease MG468, and MG468.1. There is no predicted substrate binding p [...]